Zelcer N - Search Results

1

Regulation of intestinal LDLR by the LXR-IDOL axis.

van Loon NM, van Wouw SAE, Ottenhoff R, Nelson JK, Kingma J, Scheij S, Moeton M, Zelcer N. van Loon NM, et al. Among authors: zelcer n. Atherosclerosis. 2020 Dec;315:1-9. doi: 10.1016/j.atherosclerosis.2020.10.898. Epub 2020 Nov 9. Atherosclerosis. 2020. PMID: 33190106 Free article.

2

Distinct functional domains contribute to degradation of the low density lipoprotein receptor (LDLR) by the E3 ubiquitin ligase inducible Degrader of the LDLR (IDOL).

Sorrentino V, Scheer L, Santos A, Reits E, Bleijlevens B, Zelcer N. Sorrentino V, et al. Among authors: zelcer n. J Biol Chem. 2011 Aug 26;286(34):30190-9. doi: 10.1074/jbc.M111.249557. Epub 2011 Jul 6. J Biol Chem. 2011. PMID: 21734303 Free PMC article.

3

Post-transcriptional regulation of lipoprotein receptors by the E3-ubiquitin ligase inducible degrader of the low-density lipoprotein receptor.

Sorrentino V, Zelcer N. Sorrentino V, et al. Among authors: zelcer n. Curr Opin Lipidol. 2012 Jun;23(3):213-219. doi: 10.1097/MOL.0b013e3283532947. Curr Opin Lipidol. 2012. PMID: 22510808 Review.

4

Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein.

Sorrentino V, Fouchier SW, Motazacker MM, Nelson JK, Defesche JC, Dallinga-Thie GM, Kastelein JJ, Kees Hovingh G, Zelcer N. Sorrentino V, et al. Among authors: zelcer n. Eur Heart J. 2013 May;34(17):1292-7. doi: 10.1093/eurheartj/ehs472. Epub 2013 Jan 16. Eur Heart J. 2013. PMID: 23324548

5

The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation.

Sorrentino V, Nelson JK, Maspero E, Marques ARA, Scheer L, Polo S, Zelcer N. Sorrentino V, et al. Among authors: zelcer n. J Lipid Res. 2013 Aug;54(8):2174-2184. doi: 10.1194/jlr.M037713. Epub 2013 Jun 3. J Lipid Res. 2013. PMID: 23733886 Free PMC article.

6

NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation.

Pietiäinen V, Vassilev B, Blom T, Wang W, Nelson J, Bittman R, Bäck N, Zelcer N, Ikonen E. Pietiäinen V, et al. Among authors: zelcer n. J Cell Sci. 2013 Sep 1;126(Pt 17):3961-71. doi: 10.1242/jcs.128132. Epub 2013 Jun 26. J Cell Sci. 2013. PMID: 23813961

7

The UPS and downs of cholesterol homeostasis.

Sharpe LJ, Cook EC, Zelcer N, Brown AJ. Sharpe LJ, et al. Among authors: zelcer n. Trends Biochem Sci. 2014 Nov;39(11):527-35. doi: 10.1016/j.tibs.2014.08.008. Epub 2014 Sep 11. Trends Biochem Sci. 2014. PMID: 25220377 Review.

8

LIM-only protein FHL2 is a positive regulator of liver X receptors in smooth muscle cells involved in lipid homeostasis.

Kurakula K, Sommer D, Sokolovic M, Moerland PD, Scheij S, van Loenen PB, Koenis DS, Zelcer N, van Tiel CM, de Vries CJ. Kurakula K, et al. Among authors: zelcer n. Mol Cell Biol. 2015 Jan;35(1):52-62. doi: 10.1128/MCB.00525-14. Epub 2014 Oct 20. Mol Cell Biol. 2015. PMID: 25332231 Free PMC article.

9

A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes.

Loregger A, Cook EC, Nelson JK, Moeton M, Sharpe LJ, Engberg S, Karimova M, Lambert G, Brown AJ, Zelcer N. Loregger A, et al. Among authors: zelcer n. Mol Cell Biol. 2015 Nov 2;36(2):285-94. doi: 10.1128/MCB.00890-15. Print 2016 Jan 15. Mol Cell Biol. 2015. PMID: 26527619 Free PMC article.

10

Identification of the (Pro)renin Receptor as a Novel Regulator of Low-Density Lipoprotein Metabolism.

Lu X, Meima ME, Nelson JK, Sorrentino V, Loregger A, Scheij S, Dekkers DH, Mulder MT, Demmers JA, M-Dallinga-Thie G, Zelcer N, Danser AH. Lu X, et al. Among authors: zelcer n. Circ Res. 2016 Jan 22;118(2):222-9. doi: 10.1161/CIRCRESAHA.115.306799. Epub 2015 Nov 18. Circ Res. 2016. PMID: 26582775

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