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A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study.
Yazici Y, McAlindon TE, Fleischmann R, Gibofsky A, Lane NE, Kivitz AJ, Skrepnik N, Armas E, Swearingen CJ, DiFrancesco A, Tambiah JRS, Hood J, Hochberg MC. Yazici Y, et al. Among authors: skrepnik n. Osteoarthritis Cartilage. 2017 Oct;25(10):1598-1606. doi: 10.1016/j.joca.2017.07.006. Epub 2017 Jul 13. Osteoarthritis Cartilage. 2017. PMID: 28711582 Free article. Clinical Trial.
A Phase 2b randomized trial of lorecivivint, a novel intra-articular CLK2/DYRK1A inhibitor and Wnt pathway modulator for knee osteoarthritis.
Yazici Y, McAlindon TE, Gibofsky A, Lane NE, Lattermann C, Skrepnik N, Swearingen CJ, Simsek I, Ghandehari H, DiFrancesco A, Gibbs J, Tambiah JRS, Hochberg MC. Yazici Y, et al. Among authors: skrepnik n. Osteoarthritis Cartilage. 2021 May;29(5):654-666. doi: 10.1016/j.joca.2021.02.004. Epub 2021 Feb 12. Osteoarthritis Cartilage. 2021. PMID: 33588087 Free article. Clinical Trial.
Intra-articular hylastan versus steroid for knee osteoarthritis.
Housman L, Arden N, Schnitzer TJ, Birbara C, Conrozier T, Skrepnik N, Wei N, Bockow B, Waddell D, Tahir H, Hammond A, Goupille P, Sanson BJ, Elkins C, Bailleul F. Housman L, et al. Among authors: skrepnik n. Knee Surg Sports Traumatol Arthrosc. 2014 Jul;22(7):1684-92. doi: 10.1007/s00167-013-2438-7. Epub 2013 Feb 16. Knee Surg Sports Traumatol Arthrosc. 2014. PMID: 23417236 Clinical Trial.
A Novel Mobile App-based Neuromuscular Electrical Stimulation Therapy for the Management of Knee Osteoarthritis: Results From an Extension Study of a Randomized, Double-blind, Sham-controlled, Multicenter Trial.
Dasa V, Skrepnik NV, Petersen D, Delanois RE. Dasa V, et al. Among authors: skrepnik nv. J Am Acad Orthop Surg Glob Res Rev. 2022 Sep 12;6(9):e22.00115. doi: 10.5435/JAAOSGlobal-D-22-00115. eCollection 2022 Sep 1. J Am Acad Orthop Surg Glob Res Rev. 2022. PMID: 36094457 Free PMC article. Clinical Trial.
Evaluating the use of intra-articular injections as a treatment for painful hip osteoarthritis: a randomized, double-blind, multicenter, parallel-group study comparing a single 6-mL injection of hylan G-F 20 with saline.
Brander V, Skrepnik N, Petrella RJ, Jiang GL, Accomando B, Vardanyan A. Brander V, et al. Among authors: skrepnik n. Osteoarthritis Cartilage. 2019 Jan;27(1):59-70. doi: 10.1016/j.joca.2018.08.018. Epub 2018 Sep 14. Osteoarthritis Cartilage. 2019. PMID: 30223023 Free article. Clinical Trial.
A Novel Mobile App-Based Neuromuscular Electrical Stimulation Therapy for Improvement of Knee Pain, Stiffness, and Function in Knee Osteoarthritis: A Randomized Trial.
Sax OC, Gesheff MG, Mahajan A, Patel N, Andrews TJ, Jreisat A, Ajani D, McMullen D, Mbogua C, Petersen D, Dasa V, Skrepnik N, Delanois RE. Sax OC, et al. Among authors: skrepnik n. Arthroplast Today. 2022 Apr 27;15:125-131. doi: 10.1016/j.artd.2022.03.007. eCollection 2022 Jun. Arthroplast Today. 2022. PMID: 35514364 Free PMC article.
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