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Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Wellner A, et al. Among authors: wingler lm. bioRxiv [Preprint]. 2020 Nov 11:2020.11.11.378778. doi: 10.1101/2020.11.11.378778. bioRxiv. 2020. Update in: Nat Chem Biol. 2021 Oct;17(10):1057-1064. doi: 10.1038/s41589-021-00832-4 PMID: 33200136 Free PMC article. Updated. Preprint.
Rapid generation of potent antibodies by autonomous hypermutation in yeast.
Wellner A, McMahon C, Gilman MSA, Clements JR, Clark S, Nguyen KM, Ho MH, Hu VJ, Shin JE, Feldman J, Hauser BM, Caradonna TM, Wingler LM, Schmidt AG, Marks DS, Abraham J, Kruse AC, Liu CC. Wellner A, et al. Among authors: wingler lm. Nat Chem Biol. 2021 Oct;17(10):1057-1064. doi: 10.1038/s41589-021-00832-4. Epub 2021 Jun 24. Nat Chem Biol. 2021. PMID: 34168368 Free PMC article.
Synthetic nanobodies as angiotensin receptor blockers.
McMahon C, Staus DP, Wingler LM, Wang J, Skiba MA, Elgeti M, Hubbell WL, Rockman HA, Kruse AC, Lefkowitz RJ. McMahon C, et al. Among authors: wingler lm. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20284-20291. doi: 10.1073/pnas.2009029117. Epub 2020 Aug 4. Proc Natl Acad Sci U S A. 2020. PMID: 32753386 Free PMC article.
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation.
Staus DP, Strachan RT, Manglik A, Pani B, Kahsai AW, Kim TH, Wingler LM, Ahn S, Chatterjee A, Masoudi A, Kruse AC, Pardon E, Steyaert J, Weis WI, Prosser RS, Kobilka BK, Costa T, Lefkowitz RJ. Staus DP, et al. Among authors: wingler lm. Nature. 2016 Jul 21;535(7612):448-52. doi: 10.1038/nature18636. Epub 2016 Jul 13. Nature. 2016. PMID: 27409812 Free PMC article.
β-Arrestin-Biased Angiotensin II Receptor Agonists for COVID-19.
Manglik A, Wingler LM, Rockman HA, Lefkowitz RJ. Manglik A, et al. Among authors: wingler lm. Circulation. 2020 Jul 28;142(4):318-320. doi: 10.1161/CIRCULATIONAHA.120.048723. Epub 2020 May 15. Circulation. 2020. PMID: 32412788 Free PMC article. Review. No abstract available.
31 results