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Phase 1 randomized study on the safety, tolerability, and pharmacodynamic cognitive and electrophysiological effects of a dopamine D1 receptor positive allosteric modulator in patients with schizophrenia.
Desai A, Benner L, Wu R, Gertsik L, Maruff P, Light GA, Uz T, Marek GJ, Zhu T. Desai A, et al. Among authors: maruff p. Neuropsychopharmacology. 2021 May;46(6):1145-1151. doi: 10.1038/s41386-020-00908-0. Epub 2020 Nov 17. Neuropsychopharmacology. 2021. PMID: 33203954 Free PMC article. Clinical Trial.
A Phase II study of a histamine H₃ receptor antagonist GSK239512 for cognitive impairment in stable schizophrenia subjects on antipsychotic therapy.
Jarskog LF, Lowy MT, Grove RA, Keefe RS, Horrigan JP, Ball MP, Breier A, Buchanan RW, Carter CS, Csernansky JG, Goff DC, Green MF, Kantrowitz JT, Keshavan MS, Laurelle M, Lieberman JA, Marder SR, Maruff P, McMahon RP, Seidman LJ, Peykamian MA. Jarskog LF, et al. Among authors: maruff p. Schizophr Res. 2015 May;164(1-3):136-42. doi: 10.1016/j.schres.2015.01.041. Epub 2015 Feb 24. Schizophr Res. 2015. PMID: 25728831 Clinical Trial.
A phase 1b/2a multicenter study of the safety and preliminary pharmacodynamic effects of selective muscarinic M1 receptor agonist HTL0018318 in patients with mild-to-moderate Alzheimer's disease.
Nathan PJ, Millais SB, Godwood A, Dewit O, Cross DM, Liptrot J, Ruparelia B, Jones SP, Bakker G, Maruff PT, Light GA, Brown AJH, Weir MP, Congreve M, Tasker T. Nathan PJ, et al. Alzheimers Dement (N Y). 2022 Feb 23;8(1):e12273. doi: 10.1002/trc2.12273. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35229025 Free PMC article.
Saccade and cognitive function in chronic kava users.
Cairney S, Clough AR, Maruff P, Collie A, Currie BJ, Currie J. Cairney S, et al. Among authors: maruff p. Neuropsychopharmacology. 2003 Feb;28(2):389-96. doi: 10.1038/sj.npp.1300052. Neuropsychopharmacology. 2003. PMID: 12589393
532 results