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Potential Role of Oral Rinses Targeting the Viral Lipid Envelope in SARS-CoV-2 Infection.
O'Donnell VB, Thomas D, Stanton R, Maillard JY, Murphy RC, Jones SA, Humphreys I, Wakelam MJO, Fegan C, Wise MP, Bosch A, Sattar SA. O'Donnell VB, et al. Among authors: humphreys i. Function (Oxf). 2020;1(1):zqaa002. doi: 10.1093/function/zqaa002. Epub 2020 Jun 5. Function (Oxf). 2020. PMID: 33215159 Free PMC article. Review.
Interleukin-6 signaling drives fibrosis in unresolved inflammation.
Fielding CA, Jones GW, McLoughlin RM, McLeod L, Hammond VJ, Uceda J, Williams AS, Lambie M, Foster TL, Liao CT, Rice CM, Greenhill CJ, Colmont CS, Hams E, Coles B, Kift-Morgan A, Newton Z, Craig KJ, Williams JD, Williams GT, Davies SJ, Humphreys IR, O'Donnell VB, Taylor PR, Jenkins BJ, Topley N, Jones SA. Fielding CA, et al. Immunity. 2014 Jan 16;40(1):40-50. doi: 10.1016/j.immuni.2013.10.022. Epub 2014 Jan 9. Immunity. 2014. PMID: 24412616 Free PMC article.
SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies.
Fielding CA, Sabberwal P, Williamson JC, Greenwood EJD, Crozier TWM, Zelek W, Seow J, Graham C, Huettner I, Edgeworth JD, Price DA, Morgan PB, Ladell K, Eberl M, Humphreys IR, Merrick B, Doores K, Wilson SJ, Lehner PJ, Wang ECY, Stanton RJ. Fielding CA, et al. Among authors: humphreys ir. Elife. 2022 May 19;11:e74489. doi: 10.7554/eLife.74489. Elife. 2022. PMID: 35587364 Free PMC article.
Neutrophils recruited by IL-22 in peripheral tissues function as TRAIL-dependent antiviral effectors against MCMV.
Stacey MA, Marsden M, Pham N TA, Clare S, Dolton G, Stack G, Jones E, Klenerman P, Gallimore AM, Taylor PR, Snelgrove RJ, Lawley TD, Dougan G, Benedict CA, Jones SA, Wilkinson GW, Humphreys IR. Stacey MA, et al. Cell Host Microbe. 2014 Apr 9;15(4):471-83. doi: 10.1016/j.chom.2014.03.003. Cell Host Microbe. 2014. PMID: 24721575 Free PMC article.
CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue.
Stack G, Jones E, Marsden M, Stacey MA, Snelgrove RJ, Lacaze P, Jacques LC, Cuff SM, Stanton RJ, Gallimore AM, Hussell T, Wilkinson GW, Ghazal P, Taylor PR, Humphreys IR. Stack G, et al. PLoS Pathog. 2015 Feb 5;11(2):e1004641. doi: 10.1371/journal.ppat.1004641. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25654642 Free PMC article.
196 results