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Stepwise Promoter Melting by Bacterial RNA Polymerase.
Chen J, Chiu C, Gopalkrishnan S, Chen AY, Olinares PDB, Saecker RM, Winkelman JT, Maloney MF, Chait BT, Ross W, Gourse RL, Campbell EA, Darst SA. Chen J, et al. Among authors: saecker rm. Mol Cell. 2020 Apr 16;78(2):275-288.e6. doi: 10.1016/j.molcel.2020.02.017. Epub 2020 Mar 10. Mol Cell. 2020. PMID: 32160514 Free PMC article.
Time-resolved cryo-EM using Spotiton.
Dandey VP, Budell WC, Wei H, Bobe D, Maruthi K, Kopylov M, Eng ET, Kahn PA, Hinshaw JE, Kundu N, Nimigean CM, Fan C, Sukomon N, Darst SA, Saecker RM, Chen J, Malone B, Potter CS, Carragher B. Dandey VP, et al. Among authors: saecker rm. Nat Methods. 2020 Sep;17(9):897-900. doi: 10.1038/s41592-020-0925-6. Epub 2020 Aug 10. Nat Methods. 2020. PMID: 32778833 Free PMC article.
Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy.
Saecker RM, Mueller AU, Malone B, Chen J, Budell WC, Dandey VP, Maruthi K, Mendez JH, Molina N, Eng ET, Yen LY, Potter CS, Carragher B, Darst SA. Saecker RM, et al. bioRxiv [Preprint]. 2024 Mar 14:2024.03.13.584744. doi: 10.1101/2024.03.13.584744. bioRxiv. 2024. Update in: Nat Struct Mol Biol. 2024 Nov;31(11):1778-1788. doi: 10.1038/s41594-024-01349-9 PMID: 38559232 Free PMC article. Updated. Preprint.
37 results