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Functionalized pyrazoles and pyrazolo[3,4-d]pyridazinones: Synthesis and evaluation of their phosphodiesterase 4 inhibitory activity.
Biagini P, Biancalani C, Graziano A, Cesari N, Giovannoni MP, Cilibrizzi A, Dal Piaz V, Vergelli C, Crocetti L, Delcanale M, Armani E, Rizzi A, Puccini P, Gallo PM, Spinabelli D, Caruso P. Biagini P, et al. Among authors: crocetti l. Bioorg Med Chem. 2010 May 15;18(10):3506-17. doi: 10.1016/j.bmc.2010.03.066. Epub 2010 Mar 31. Bioorg Med Chem. 2010. PMID: 20413313
Synthesis, enantioresolution, and activity profile of chiral 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones as potent N-formyl peptide receptor agonists.
Cilibrizzi A, Schepetkin IA, Bartolucci G, Crocetti L, Dal Piaz V, Giovannoni MP, Graziano A, Kirpotina LN, Quinn MT, Vergelli C. Cilibrizzi A, et al. Among authors: crocetti l. Bioorg Med Chem. 2012 Jun 15;20(12):3781-92. doi: 10.1016/j.bmc.2012.04.043. Epub 2012 Apr 27. Bioorg Med Chem. 2012. PMID: 22607879 Free PMC article.
Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists.
Giovannoni MP, Schepetkin IA, Cilibrizzi A, Crocetti L, Khlebnikov AI, Dahlgren C, Graziano A, Dal Piaz V, Kirpotina LN, Zerbinati S, Vergelli C, Quinn MT. Giovannoni MP, et al. Among authors: crocetti l. Eur J Med Chem. 2013 Jun;64:512-28. doi: 10.1016/j.ejmech.2013.03.066. Epub 2013 Apr 8. Eur J Med Chem. 2013. PMID: 23685570 Free PMC article.
141 results