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Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer.
Suzuki Y, Ng SB, Chua C, Leow WQ, Chng J, Liu SY, Ramnarayanan K, Gan A, Ho DL, Ten R, Su Y, Lezhava A, Lai JH, Koh D, Lim KH, Tan P, Rozen SG, Tan IB. Suzuki Y, et al. Among authors: ng sb. Mol Oncol. 2017 Feb;11(2):124-139. doi: 10.1002/1878-0261.12012. Epub 2016 Oct 20. Mol Oncol. 2017. PMID: 28145097 Free PMC article. Clinical Trial.
Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden.
Zhu G, Guo YA, Ho D, Poon P, Poh ZW, Wong PM, Gan A, Chang MM, Kleftogiannis D, Lau YT, Tay B, Lim WJ, Chua C, Tan TJ, Koo SL, Chong DQ, Yap YS, Tan I, Ng S, Skanderup AJ. Zhu G, et al. Nat Commun. 2021 Apr 13;12(1):2229. doi: 10.1038/s41467-021-22463-y. Nat Commun. 2021. PMID: 33850132 Free PMC article.
Massively parallel sequencing and rare disease.
Ng SB, Nickerson DA, Bamshad MJ, Shendure J. Ng SB, et al. Hum Mol Genet. 2010 Oct 15;19(R2):R119-24. doi: 10.1093/hmg/ddq390. Epub 2010 Sep 15. Hum Mol Genet. 2010. PMID: 20846941 Free PMC article. Review.
Haplotype-resolved genome sequencing of a Gujarati Indian individual.
Kitzman JO, Mackenzie AP, Adey A, Hiatt JB, Patwardhan RP, Sudmant PH, Ng SB, Alkan C, Qiu R, Eichler EE, Shendure J. Kitzman JO, et al. Among authors: ng sb. Nat Biotechnol. 2011 Jan;29(1):59-63. doi: 10.1038/nbt.1740. Epub 2010 Dec 19. Nat Biotechnol. 2011. PMID: 21170042 Free PMC article.
Determination of isoform-specific RNA structure with nanopore long reads.
Aw JGA, Lim SW, Wang JX, Lambert FRP, Tan WT, Shen Y, Zhang Y, Kaewsapsak P, Li C, Ng SB, Vardy LA, Tan MH, Nagarajan N, Wan Y. Aw JGA, et al. Among authors: ng sb. Nat Biotechnol. 2021 Mar;39(3):336-346. doi: 10.1038/s41587-020-0712-z. Epub 2020 Oct 26. Nat Biotechnol. 2021. PMID: 33106685
195 results