Locasale JW - Search Results

1

SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease.

Gut P, Matilainen S, Meyer JG, Pällijeff P, Richard J, Carroll CJ, Euro L, Jackson CB, Isohanni P, Minassian BA, Alkhater RA, Østergaard E, Civiletto G, Parisi A, Thevenet J, Rardin MJ, He W, Nishida Y, Newman JC, Liu X, Christen S, Moco S, Locasale JW, Schilling B, Suomalainen A, Verdin E. Gut P, et al. Among authors: locasale jw. Nat Commun. 2020 Nov 23;11(1):5927. doi: 10.1038/s41467-020-19743-4. Nat Commun. 2020. PMID: 33230181 Free PMC article.

2

High-Resolution Metabolomics with Acyl-CoA Profiling Reveals Widespread Remodeling in Response to Diet.

Liu X, Sadhukhan S, Sun S, Wagner GR, Hirschey MD, Qi L, Lin H, Locasale JW. Liu X, et al. Among authors: locasale jw. Mol Cell Proteomics. 2015 Jun;14(6):1489-500. doi: 10.1074/mcp.M114.044859. Epub 2015 Mar 20. Mol Cell Proteomics. 2015. PMID: 25795660 Free PMC article.

3

The rate of glycolysis quantitatively mediates specific histone acetylation sites.

Cluntun AA, Huang H, Dai L, Liu X, Zhao Y, Locasale JW. Cluntun AA, et al. Among authors: locasale jw. Cancer Metab. 2015 Sep 23;3:10. doi: 10.1186/s40170-015-0135-3. eCollection 2015. Cancer Metab. 2015. PMID: 26401273 Free PMC article.

4

Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function.

Sadhukhan S, Liu X, Ryu D, Nelson OD, Stupinski JA, Li Z, Chen W, Zhang S, Weiss RS, Locasale JW, Auwerx J, Lin H. Sadhukhan S, et al. Among authors: locasale jw. Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4320-5. doi: 10.1073/pnas.1519858113. Epub 2016 Apr 5. Proc Natl Acad Sci U S A. 2016. PMID: 27051063 Free PMC article.

5

Integrative modelling of tumour DNA methylation quantifies the contribution of metabolism.

Mehrmohamadi M, Mentch LK, Clark AG, Locasale JW. Mehrmohamadi M, et al. Among authors: locasale jw. Nat Commun. 2016 Dec 14;7:13666. doi: 10.1038/ncomms13666. Nat Commun. 2016. PMID: 27966532 Free PMC article.

6

Metabolomics: A Primer.

Liu X, Locasale JW. Liu X, et al. Among authors: locasale jw. Trends Biochem Sci. 2017 Apr;42(4):274-284. doi: 10.1016/j.tibs.2017.01.004. Epub 2017 Feb 11. Trends Biochem Sci. 2017. PMID: 28196646 Free PMC article. Review.

7

Metabolomics reveals intratumor heterogeneity - Implications for precision medicine.

Liu X, Locasale JW. Liu X, et al. Among authors: locasale jw. EBioMedicine. 2017 May;19:4-5. doi: 10.1016/j.ebiom.2017.04.030. Epub 2017 Apr 24. EBioMedicine. 2017. PMID: 28457617 Free PMC article. No abstract available.

8

Biochemistry: A toxin that fuels metabolism.

Liu X, Locasale JW. Liu X, et al. Among authors: locasale jw. Nature. 2017 Aug 31;548(7669):533-534. doi: 10.1038/nature23541. Epub 2017 Aug 16. Nature. 2017. PMID: 28813408 No abstract available.

9

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated T_reg subsets to protect tissue homeostasis.

Chapman NM, Zeng H, Nguyen TM, Wang Y, Vogel P, Dhungana Y, Liu X, Neale G, Locasale JW, Chi H. Chapman NM, et al. Among authors: locasale jw. Nat Commun. 2018 May 29;9(1):2095. doi: 10.1038/s41467-018-04392-5. Nat Commun. 2018. PMID: 29844370 Free PMC article.

10

Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism.

Reid MA, Allen AE, Liu S, Liberti MV, Liu P, Liu X, Dai Z, Gao X, Wang Q, Liu Y, Lai L, Locasale JW. Reid MA, et al. Among authors: locasale jw. Nat Commun. 2018 Dec 21;9(1):5442. doi: 10.1038/s41467-018-07868-6. Nat Commun. 2018. PMID: 30575741 Free PMC article.

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