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KRAS-regulated glutamine metabolism requires UCP2-mediated aspartate transport to support pancreatic cancer growth.
Raho S, Capobianco L, Malivindi R, Vozza A, Piazzolla C, De Leonardis F, Gorgoglione R, Scarcia P, Pezzuto F, Agrimi G, Barile SN, Pisano I, Reshkin SJ, Greco MR, Cardone RA, Rago V, Li Y, Marobbio CMT, Sommergruber W, Riley CL, Lasorsa FM, Mills E, Vegliante MC, De Benedetto GE, Fratantonio D, Palmieri L, Dolce V, Fiermonte G. Raho S, et al. Among authors: barile sn. Nat Metab. 2020 Dec;2(12):1373-1381. doi: 10.1038/s42255-020-00315-1. Epub 2020 Nov 23. Nat Metab. 2020. PMID: 33230296
Statins Reduce Intratumor Cholesterol Affecting Adrenocortical Cancer Growth.
Trotta F, Avena P, Chimento A, Rago V, De Luca A, Sculco S, Nocito MC, Malivindi R, Fallo F, Pezzani R, Pilon C, Lasorsa FM, Barile SN, Palmieri L, Lerario AM, Pezzi V, Casaburi I, Sirianni R. Trotta F, et al. Among authors: barile sn. Mol Cancer Ther. 2020 Sep;19(9):1909-1921. doi: 10.1158/1535-7163.MCT-19-1063. Epub 2020 Jun 16. Mol Cancer Ther. 2020. PMID: 32546662
Histone Acetylation Defects in Brain Precursor Cells: A Potential Pathogenic Mechanism Causing Proliferation and Differentiation Dysfunctions in Mitochondrial Aspartate-Glutamate Carrier Isoform 1 Deficiency.
Poeta E, Petralla S, Babini G, Renzi B, Celauro L, Magnifico MC, Barile SN, Masotti M, De Chirico F, Massenzio F, Viggiano L, Palmieri L, Virgili M, Lasorsa FM, Monti B. Poeta E, et al. Among authors: barile sn. Front Cell Neurosci. 2022 Jan 12;15:773709. doi: 10.3389/fncel.2021.773709. eCollection 2021. Front Cell Neurosci. 2022. PMID: 35095421 Free PMC article.
Deficiency of Mitochondrial Aspartate-Glutamate Carrier 1 Leads to Oligodendrocyte Precursor Cell Proliferation Defects Both In Vitro and In Vivo.
Petralla S, Peña-Altamira LE, Poeta E, Massenzio F, Virgili M, Barile SN, Sbano L, Profilo E, Corricelli M, Danese A, Giorgi C, Ostan R, Capri M, Pinton P, Palmieri F, Lasorsa FM, Monti B. Petralla S, et al. Among authors: barile sn. Int J Mol Sci. 2019 Sep 11;20(18):4486. doi: 10.3390/ijms20184486. Int J Mol Sci. 2019. PMID: 31514314 Free PMC article.
20 results