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179,894 results

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Eradication of T-ALL Cells by CD7-targeted Universal CAR-T Cells and Initial Test of Ruxolitinib-based CRS Management.
Li S, Wang X, Yuan Z, Liu L, Luo L, Li Y, Wu K, Liu J, Yang C, Li Z, Wang D, Shen L, Ye X, He J, Han C, Wang Y, Zhang D, Dong Y, Fang L, Chen Y, Sersch M, Cao WW, Wang S. Li S, et al. Among authors: chen y. Clin Cancer Res. 2021 Mar 1;27(5):1242-1246. doi: 10.1158/1078-0432.CCR-20-1271. Epub 2020 Nov 24. Clin Cancer Res. 2021. PMID: 33234511
CD7 targeted "off-the-shelf" CAR-T demonstrates robust in vivo expansion and high efficacy in the treatment of patients with relapsed and refractory T cell malignancies.
Li S, Wang X, Liu L, Liu J, Rao J, Yuan Z, Gao L, Li Y, Luo L, Li G, Li Z, Li S, He J, Zhang L, Chen L, Huang W, Yin P, Li C, Li X, Wang Y, Dong Y, Zhang D, Zang Q, Chen Y, Shen L, Li W, Cao W, Zhang X, Wang S. Li S, et al. Among authors: chen l, chen y. Leukemia. 2023 Nov;37(11):2176-2186. doi: 10.1038/s41375-023-02018-4. Epub 2023 Sep 12. Leukemia. 2023. PMID: 37700087
Modified lentiviral globin gene therapy for pediatric β00 transfusion-dependent β-thalassemia: A single-center, single-arm pilot trial.
Li S, Ling S, Wang D, Wang X, Hao F, Yin L, Yuan Z, Liu L, Zhang L, Li Y, Chen Y, Luo L, Dai Y, Zhang L, Chen L, Deng D, Tang W, Zhang S, Wang S, Cai Y. Li S, et al. Among authors: chen l, chen y. Cell Stem Cell. 2024 Jul 5;31(7):961-973.e8. doi: 10.1016/j.stem.2024.04.021. Epub 2024 May 16. Cell Stem Cell. 2024. PMID: 38759653 Free article. Clinical Trial.
Stable engraftment, as well as graft versus host disease-free and relapse-free survival brought by the combination of CD7 targeted universal chimeric antigen receptor-T, and donor hemopoietic stem cells: Indication of a case report.
Li S, Yuan Z, Liu L, Li Y, Luo L, Peng L, Xu M, Yin P, Chen Y, Li X, Zang Q, Zhang X, Wang S. Li S, et al. Among authors: chen y. EJHaem. 2024 May 15;5(3):584-588. doi: 10.1002/jha2.914. eCollection 2024 Jun. EJHaem. 2024. PMID: 38895056 Free PMC article.
Fludarabine, busulfan, and melphalan conditioning regimen in allogeneic hematopoietic stem cell transplantation for adult patients with myeloid malignancies: A multicenter retrospective study.
Jiang J, Li X, Wu D, Lu Q, Miao K, Wang H, Li X, Chen Y, Zhou S, Zhou Y, Liao G, Jiang C, Yuan X, Zhao Y, Chang C, Chen J, Zhu H, Ma R, Li N, Yin X, Wu X, Wang S, Wang C, Hu J. Jiang J, et al. Among authors: chen j, chen y. EJHaem. 2024 Jul 8;5(4):757-767. doi: 10.1002/jha2.947. eCollection 2024 Aug. EJHaem. 2024. PMID: 39157627 Free PMC article.
Engineered extracellular vesicles with DR5 agonistic scFvs simultaneously target tumor and immunosuppressive stromal cells.
Guo Y, Wang H, Liu S, Zhang X, Zhu X, Huang L, Zhong W, Guan L, Chen Y, Xiao M, Ou L, Yang J, Chen X, Huang AC, Mitchell T, Amaravadi R, Karakousis G, Miura J, Schuchter L, Flowers A, Zheng Q, Mou H, Gimotty P, Herlyn M, Guo W, Xu X. Guo Y, et al. Among authors: chen y. Sci Adv. 2025 Jan 17;11(3):eadp9009. doi: 10.1126/sciadv.adp9009. Epub 2025 Jan 15. Sci Adv. 2025. PMID: 39813334
CFTR dictates monocyte adhesion by facilitating integrin clustering but not activation.
Younis DA, Marosvari M, Liu W, Pulikkot S, Cao Z, Zhou B, Vella AT, McArdle S, Hu L, Chen Y, Gan W, Yu J, Bruscia EM, Fan Z. Younis DA, et al. Among authors: chen y. Proc Natl Acad Sci U S A. 2025 Jan 21;122(3):e2412717122. doi: 10.1073/pnas.2412717122. Epub 2025 Jan 15. Proc Natl Acad Sci U S A. 2025. PMID: 39813254
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