Yue Z - Search Results

1

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.

Wang M, Li A, Sekiya M, Beckmann ND, Quan X, Schrode N, Fernando MB, Yu A, Zhu L, Cao J, Lyu L, Horgusluoglu E, Wang Q, Guo L, Wang YS, Neff R, Song WM, Wang E, Shen Q, Zhou X, Ming C, Ho SM, Vatansever S, Kaniskan HÜ, Jin J, Zhou MM, Ando K, Ho L, Slesinger PA, Yue Z, Zhu J, Katsel P, Gandy S, Ehrlich ME, Fossati V, Noggle S, Cai D, Haroutunian V, Iijima KM, Schadt E, Brennand KJ, Zhang B. Wang M, et al. Among authors: yue z. Neuron. 2021 Jan 20;109(2):257-272.e14. doi: 10.1016/j.neuron.2020.11.002. Epub 2020 Nov 24. Neuron. 2021. PMID: 33238137 Free PMC article.

2

Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.

Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Fraser P, Westaway D, St George-Hyslop PH, Szabo P, Relkin NR, Buxbaum JD, Glabe CG, Protter AA, Martins RN, Ehrlich ME, Petsko GA, Yue Z, Gandy S. Steele JW, et al. Among authors: yue z. Mol Psychiatry. 2013 Aug;18(8):889-97. doi: 10.1038/mp.2012.106. Epub 2012 Jul 31. Mol Psychiatry. 2013. PMID: 22850627 Free PMC article.

3

Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.

Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Protter AA, Martins RN, Ehrlich ME, Yue Z, Petsko GA, Gandy S. Steele JW, et al. Among authors: yue z. Mol Psychiatry. 2013 Aug;18(8):882-8. doi: 10.1038/mp.2012.115. Epub 2012 Aug 7. Mol Psychiatry. 2013. PMID: 22869031 Free PMC article.

4

Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons.

Pan PY, Li X, Wang J, Powell J, Wang Q, Zhang Y, Chen Z, Wicinski B, Hof P, Ryan TA, Yue Z. Pan PY, et al. Among authors: yue z. J Neurosci. 2017 Nov 22;37(47):11366-11376. doi: 10.1523/JNEUROSCI.0964-17.2017. Epub 2017 Oct 20. J Neurosci. 2017. PMID: 29054882 Free PMC article.

5

The landscape of multiscale transcriptomic networks and key regulators in Parkinson's disease.

Wang Q, Zhang Y, Wang M, Song WM, Shen Q, McKenzie A, Choi I, Zhou X, Pan PY, Yue Z, Zhang B. Wang Q, et al. Among authors: yue z. Nat Commun. 2019 Nov 20;10(1):5234. doi: 10.1038/s41467-019-13144-y. Nat Commun. 2019. PMID: 31748532 Free PMC article.

6

Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice.

Lachance V, Wang Q, Sweet E, Choi I, Cai CZ, Zhuang XX, Zhang Y, Jiang JL, Blitzer RD, Bozdagi-Gunal O, Zhang B, Lu JH, Yue Z. Lachance V, et al. Among authors: yue z. Mol Neurodegener. 2019 Nov 27;14(1):43. doi: 10.1186/s13024-019-0342-4. Mol Neurodegener. 2019. PMID: 31775806 Free PMC article.

7

Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.

Choi I, Zhang Y, Seegobin SP, Pruvost M, Wang Q, Purtell K, Zhang B, Yue Z. Choi I, et al. Among authors: yue z. Nat Commun. 2020 Mar 13;11(1):1386. doi: 10.1038/s41467-020-15119-w. Nat Commun. 2020. PMID: 32170061 Free PMC article.

8

Synj1 haploinsufficiency causes dopamine neuron vulnerability and alpha-synuclein accumulation in mice.

Pan PY, Sheehan P, Wang Q, Zhu X, Zhang Y, Choi I, Li X, Saenz J, Zhu J, Wang J, El Gaamouch F, Zhu L, Cai D, Yue Z. Pan PY, et al. Among authors: yue z. Hum Mol Genet. 2020 Aug 11;29(14):2300-2312. doi: 10.1093/hmg/ddaa080. Hum Mol Genet. 2020. PMID: 32356558 Free PMC article.

9

Disentangling the Molecular Pathways of Parkinson's Disease using Multiscale Network Modeling.

Wang Q, Zhang B, Yue Z. Wang Q, et al. Among authors: yue z. Trends Neurosci. 2021 Mar;44(3):182-188. doi: 10.1016/j.tins.2020.11.006. Trends Neurosci. 2021. PMID: 33358606 Free PMC article. Review.

10

Association of neurogranin gene expression with Alzheimer's disease pathology in the perirhinal cortex.

Sun X, Wang Q, Blennow K, Zetterberg H, McCarthy M, Loewenstein DA, Vontell R, Yue Z, Zhang B. Sun X, et al. Among authors: yue z. Alzheimers Dement (N Y). 2021 Apr 9;7(1):e12162. doi: 10.1002/trc2.12162. eCollection 2021. Alzheimers Dement (N Y). 2021. PMID: 33860070 Free PMC article.

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