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Cigarette Smoke Affects Dendritic Cell Populations, Epithelial Barrier Function, and the Immune Response to Viral Infection With H1N1.
Danov O, Wolff M, Bartel S, Böhlen S, Obernolte H, Wronski S, Jonigk D, Hammer B, Kovacevic D, Reuter S, Krauss-Etschmann S, Sewald K. Danov O, et al. Among authors: obernolte h. Front Med (Lausanne). 2020 Nov 6;7:571003. doi: 10.3389/fmed.2020.571003. eCollection 2020. Front Med (Lausanne). 2020. PMID: 33240904 Free PMC article.
BI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.
Lamb DJ, Wollin SL, Schnapp A, Bischoff D, Erb KJ, Bouyssou T, Guilliard B, Strasser C, Wex E, Blum S, Thaler E, Nickel H, Radmacher O, Haas H, Swantek JL, Souza D, Canfield M, White D, Panzenbeck M, Kashem MA, Sanville-Ross M, Kono T, Sewald K, Braun A, Obernolte H, Danov O, Schaenzle G, Rast G, Maier GM, Hoffmann M. Lamb DJ, et al. Among authors: obernolte h. J Pharmacol Exp Ther. 2016 Jun;357(3):554-61. doi: 10.1124/jpet.116.233155. Epub 2016 Apr 5. J Pharmacol Exp Ther. 2016. PMID: 27048659
Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs.
Danov O, Jiménez Delgado SM, Obernolte H, Seehase S, Dehmel S, Braubach P, Fieguth HG, Matschiner G, Fitzgerald M, Jonigk D, Knauf S, Pfennig O, Warnecke G, Wichmann J, Braun A, Sewald K. Danov O, et al. Among authors: obernolte h. PLoS One. 2018 Nov 30;13(11):e0207767. doi: 10.1371/journal.pone.0207767. eCollection 2018. PLoS One. 2018. PMID: 30500834 Free PMC article.
Human ex vivo and in vitro disease models to study food allergy.
Hung L, Obernolte H, Sewald K, Eiwegger T. Hung L, et al. Among authors: obernolte h. Asia Pac Allergy. 2019 Jan 15;9(1):e4. doi: 10.5415/apallergy.2019.9.e4. eCollection 2019 Jan. Asia Pac Allergy. 2019. PMID: 30740352 Free PMC article. Review.
Transcriptomic Analysis Reveals Priming of The Host Antiviral Interferon Signaling Pathway by Bronchobini® Resulting in Balanced Immune Response to Rhinovirus Infection in Mouse Lung Tissue Slices.
Reamon-Buettner SM, Niehof M, Hirth N, Danov O, Obernolte H, Braun A, Warnecke J, Sewald K, Wronski S. Reamon-Buettner SM, et al. Among authors: obernolte h. Int J Mol Sci. 2019 May 7;20(9):2242. doi: 10.3390/ijms20092242. Int J Mol Sci. 2019. PMID: 31067687 Free PMC article.
Rhinovirus-induced Human Lung Tissue Responses Mimic Chronic Obstructive Pulmonary Disease and Asthma Gene Signatures.
Wronski S, Beinke S, Obernolte H, Belyaev NN, Saunders KA, Lennon MG, Schaudien D, Braubach P, Jonigk D, Warnecke G, Zardo P, Fieguth HG, Wilkens L, Braun A, Hessel EM, Sewald K. Wronski S, et al. Among authors: obernolte h. Am J Respir Cell Mol Biol. 2021 Nov;65(5):544-554. doi: 10.1165/rcmb.2020-0337OC. Am J Respir Cell Mol Biol. 2021. PMID: 34181859 Free PMC article.
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