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Angiopoietin-like protein 4 deficiency augments liver fibrosis in liver diseases such as nonalcoholic steatohepatitis in mice through enhanced free cholesterol accumulation in hepatic stellate cells.
Teratani T, Tomita K, Wada A, Sugihara N, Higashiyama M, Inaba K, Horiuchi K, Hanawa Y, Nishii S, Mizoguchi A, Tanemoto R, Ito S, Okada Y, Kurihara C, Akita Y, Narimatsu K, Watanabe C, Komoto S, Oike Y, Miura S, Hokari R, Kanai T. Teratani T, et al. Among authors: kanai t. Hepatol Res. 2021 May;51(5):580-592. doi: 10.1111/hepr.13603. Epub 2021 Apr 7. Hepatol Res. 2021. PMID: 33247991
A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells.
Teratani T, Tomita K, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Tominaga S, Hiroi S, Irie R, Okada Y, Kurihara C, Ebinuma H, Saito H, Hokari R, Sugiyama K, Kanai T, Miura S, Hibi T. Teratani T, et al. Among authors: kanai t. Gastroenterology. 2012 Jan;142(1):152-164.e10. doi: 10.1053/j.gastro.2011.09.049. Epub 2011 Oct 10. Gastroenterology. 2012. PMID: 21995947
p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice.
Tomita K, Teratani T, Suzuki T, Oshikawa T, Yokoyama H, Shimamura K, Nishiyama K, Mataki N, Irie R, Minamino T, Okada Y, Kurihara C, Ebinuma H, Saito H, Shimizu I, Yoshida Y, Hokari R, Sugiyama K, Hatsuse K, Yamamoto J, Kanai T, Miura S, Hibi T. Tomita K, et al. Among authors: kanai t. J Hepatol. 2012 Oct;57(4):837-43. doi: 10.1016/j.jhep.2012.05.013. Epub 2012 May 26. J Hepatol. 2012. PMID: 22641095
Activated hepatic stellate cells mediate the differentiation of macrophages.
Chang J, Hisamatsu T, Shimamura K, Yoneno K, Adachi M, Naruse H, Igarashi T, Higuchi H, Matsuoka K, Kitazume MT, Ando S, Kamada N, Kanai T, Hibi T. Chang J, et al. Among authors: kanai t. Hepatol Res. 2013 Jun;43(6):658-69. doi: 10.1111/j.1872-034X.2012.01111.x. Epub 2012 Oct 29. Hepatol Res. 2013. PMID: 23107150
CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion.
Nakamura Y, Kanai T, Saeki K, Takabe M, Irie J, Miyoshi J, Mikami Y, Teratani T, Suzuki T, Miyata N, Hisamatsu T, Nakamoto N, Yamagishi Y, Higuchi H, Ebinuma H, Hozawa S, Saito H, Itoh H, Hibi T. Nakamura Y, et al. Among authors: kanai t. Am J Physiol Gastrointest Liver Physiol. 2013 Apr 15;304(8):G700-7. doi: 10.1152/ajpgi.00318.2012. Epub 2013 Feb 28. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23449669 Free article.
Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice.
Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Okada Y, Kurihara C, Irie R, Yokoyama H, Shimamura K, Usui S, Ebinuma H, Saito H, Watanabe C, Komoto S, Kawaguchi A, Nagao S, Sugiyama K, Hokari R, Kanai T, Miura S, Hibi T. Tomita K, et al. Among authors: kanai t. Hepatology. 2014 Jan;59(1):154-69. doi: 10.1002/hep.26604. Epub 2013 Nov 18. Hepatology. 2014. PMID: 23832448
Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells.
Tomita K, Teratani T, Suzuki T, Shimizu M, Sato H, Narimatsu K, Usui S, Furuhashi H, Kimura A, Nishiyama K, Maejima T, Okada Y, Kurihara C, Shimamura K, Ebinuma H, Saito H, Yokoyama H, Watanabe C, Komoto S, Nagao S, Sugiyama K, Aosasa S, Hatsuse K, Yamamoto J, Hibi T, Miura S, Hokari R, Kanai T. Tomita K, et al. Among authors: kanai t. J Hepatol. 2014 Jul;61(1):98-106. doi: 10.1016/j.jhep.2014.03.018. Epub 2014 Mar 18. J Hepatol. 2014. PMID: 24657401
Pregnant woman with non-comatose autoimmune acute liver failure in the second trimester rescued using medical therapy: A case report.
Sato H, Tomita K, Yasue C, Umeda R, Ebinuma H, Ogata S, Du W, Soga S, Maruta K, Yasutake Y, Narimatsu K, Usui S, Watanabe C, Komoto S, Teratani T, Suzuki T, Yokoyama H, Saito H, Nagao S, Hibi T, Miura S, Kanai T, Hokari R. Sato H, et al. Among authors: kanai t. Hepatol Res. 2015 Mar;45(3):349-55. doi: 10.1111/hepr.12344. Epub 2014 Jul 18. Hepatol Res. 2015. PMID: 24739014
Simeprevir/pegylated interferon/ribavirin triple therapy for recurrent hepatitis C after living donor liver transplantation.
Shinoda M, Ebinuma H, Itano O, Yamagishi Y, Obara H, Kitago M, Nakamoto N, Hibi T, Yagi H, Abe Y, Matsubara K, Chu PS, Wakayama Y, Taniki N, Yamaguchi A, Amemiya R, Miyake R, Mizota T, Kanai T, Kitagawa Y. Shinoda M, et al. Among authors: kanai t. Hepatol Res. 2016 Oct;46(11):1118-1128. doi: 10.1111/hepr.12666. Epub 2016 Apr 22. Hepatol Res. 2016. PMID: 26854748
1,542 results