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Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma.
Infante P, Malfanti A, Quaglio D, Balducci S, De Martin S, Bufalieri F, Mastrotto F, Basili I, Garofalo M, Lospinoso Severini L, Mori M, Manni I, Moretti M, Nicoletti C, Piaggio G, Caliceti P, Botta B, Ghirga F, Salmaso S, Di Marcotullio L. Infante P, et al. Among authors: ghirga f. Cancer Lett. 2021 Feb 28;499:220-231. doi: 10.1016/j.canlet.2020.11.028. Epub 2020 Nov 26. Cancer Lett. 2021. PMID: 33249196 Free article.
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
Infante P, Mori M, Alfonsi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D'Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L. Infante P, et al. Among authors: ghirga f. EMBO J. 2015 Jan 13;34(2):200-17. doi: 10.15252/embj.201489213. Epub 2014 Dec 4. EMBO J. 2015. PMID: 25476449 Free PMC article.
Molecular Recognition of Natural Products by Resorc[4]arene Receptors.
D'Acquarica I, Ghirga F, Quaglio D, Cerreto A, Ingallina C, Tafi A, Botta B. D'Acquarica I, et al. Among authors: ghirga f. Curr Pharm Des. 2016;22(12):1715-29. doi: 10.2174/1381612822666151211094712. Curr Pharm Des. 2016. PMID: 26654589 Review.
The Pictet-Spengler Reaction Still on Stage.
Ingallina C, D'Acquarica I, Delle Monache G, Ghirga F, Quaglio D, Ghirga P, Berardozzi S, Markovic V, Botta B. Ingallina C, et al. Among authors: ghirga p, ghirga f. Curr Pharm Des. 2016;22(12):1808-50. doi: 10.2174/1381612822666151231100247. Curr Pharm Des. 2016. PMID: 26719050 Review.
61 results