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Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Martins LC, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, Peters JK, Moritz M, Herrera N, Kratochvil HT; QCRG Structural Biology Consortium; Aimon A, Bennett JM, Neto JB, Cohen AE, Dias A, Douangamath A, Dunnett L, Fedorov O, Ferla MP, Fuchs M, Gorrie-Stone TJ, Holton JM, Johnson MG, Krojer T, Meigs G, Powell AJ; Johannes Gregor Matthias Rack; Rangel VL, Russi S, Skyner RE, Smith CA, Soares AS, Wierman JL, Zhu K, Jura N, Ashworth A, Irwin J, Thompson MC, Gestwicki JE, von Delft F, Shoichet BK, Fraser JS, Ahel I. Schuller M, et al. Among authors: johnson mg. bioRxiv [Preprint]. 2020 Nov 24:2020.11.24.393405. doi: 10.1101/2020.11.24.393405. bioRxiv. 2020. Update in: Sci Adv. 2021 Apr 14;7(16):eabf8711. doi: 10.1126/sciadv.abf8711 PMID: 33269349 Free PMC article. Updated. Preprint.
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Carvalho Martins L, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, Peters JK, Moritz M, Herrera N, Kratochvil HT; QCRG Structural Biology Consortium; Aimon A, Bennett JM, Brandao Neto J, Cohen AE, Dias A, Douangamath A, Dunnett L, Fedorov O, Ferla MP, Fuchs MR, Gorrie-Stone TJ, Holton JM, Johnson MG, Krojer T, Meigs G, Powell AJ, Rack JGM, Rangel VL, Russi S, Skyner RE, Smith CA, Soares AS, Wierman JL, Zhu K, O'Brien P, Jura N, Ashworth A, Irwin JJ, Thompson MC, Gestwicki JE, von Delft F, Shoichet BK, Fraser JS, Ahel I. Schuller M, et al. Among authors: johnson mg. Sci Adv. 2021 Apr 14;7(16):eabf8711. doi: 10.1126/sciadv.abf8711. Print 2021 Apr. Sci Adv. 2021. PMID: 33853786 Free PMC article.
Discovery of ART0380, a Potent and Selective ATR Kinase Inhibitor Undergoing Phase 2 Clinical Studies for the Treatment of Advanced or Metastatic Solid Cancers.
Carroll CL, Johnson MG, Ding Y, Kang Z, Vijayan RSK, Bardenhagen JP, Fang C, Lapointe D, Li M, Liu CY, Lv X, Ma X, Pang J, Shepard HE, Suarez C, Yau AJ, Williams CC, Wu Q, Heald RA, Robinson HMR, Smith GCM, Cross JB, Do MKG, Jiang Y, Lively S, Yap TA, Giuliani V, Heffernan T, Jones P, Di Francesco ME. Carroll CL, et al. Among authors: johnson mg. J Med Chem. 2024 Dec 26;67(24):21890-21904. doi: 10.1021/acs.jmedchem.4c01595. Epub 2024 Dec 4. J Med Chem. 2024. PMID: 39630604
Errors in the field reconstruction using CR-39 proton radiographs with high fluence variation.
Foo BC, Buschmann BI, Cufari M, Dannhoff SG, DeVault A, Evans TE, Johnson TM, Kunimune JH, Lawrence Y, Pearcy JA, Reichelt BL, Russell L, Vanderloo N, Vargas J, Wink CW, Johnson MG, Séguin FH, Petrasso RD, Frenje JA. Foo BC, et al. Among authors: johnson mg. Rev Sci Instrum. 2024 Oct 1;95(10):103527. doi: 10.1063/5.0219510. Rev Sci Instrum. 2024. PMID: 39480158
Gender differences in spine surgery for degenerative lumbar disease: prospective cohort study.
MacLean MA, Charest-Morin R, Stratton A, Singh S, Kelly AM, Pickett GE, Glennie A, Bailey C, Weber MH, Attabib N, Cherry A, Crawford E, Paquet J, Dea N, Nataraj A, Abraham E, Eseonu KC, Johnson MG, Hall H, Thomas K, McIntosh G, Fisher CG, Rampersaud YR, Greene R, Christie SD. MacLean MA, et al. Among authors: johnson mg. J Neurosurg Spine. 2024 Oct 18:1-9. doi: 10.3171/2024.7.SPINE231388. Online ahead of print. J Neurosurg Spine. 2024. PMID: 39423433
Overview of the neutron diagnostic systems for the SPARC tokamak.
Raj P, Ball JL, Carmichael J, Frenje JA, Gocht R, Gorini G, Holmes I, Johnson MG, Kennedy R, Mackie S, Nocente M, Panontin E, Petruzzo M, Rebai M, Reinke M, Rice J, Rigamonti D, Rosa MD, Saltos AA, Tardocchi M, Tinguely RA, Wang X. Raj P, et al. Among authors: johnson mg. Rev Sci Instrum. 2024 Oct 1;95(10):103507. doi: 10.1063/5.0219538. Rev Sci Instrum. 2024. PMID: 39356194
418 results