Fedorova O - Search Results

1

Structural Optimization of Polymeric Carriers to Enhance the Immunostimulatory Activity of Molecularly Defined RIG-I Agonists.

Jacobson ME, Becker KW, Palmer CR, Pastora LE, Fletcher RB, Collins KA, Fedorova O, Duvall CL, Pyle AM, Wilson JT. Jacobson ME, et al. Among authors: fedorova o. ACS Cent Sci. 2020 Nov 25;6(11):2008-2022. doi: 10.1021/acscentsci.0c00568. Epub 2020 Oct 26. ACS Cent Sci. 2020. PMID: 33274278 Free PMC article.

2

Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers.

Elion DL, Jacobson ME, Hicks DJ, Rahman B, Sanchez V, Gonzales-Ericsson PI, Fedorova O, Pyle AM, Wilson JT, Cook RS. Elion DL, et al. Among authors: fedorova o. Cancer Res. 2018 Nov 1;78(21):6183-6195. doi: 10.1158/0008-5472.CAN-18-0730. Epub 2018 Sep 17. Cancer Res. 2018. PMID: 30224377

3

Linking the group II intron catalytic domains: tertiary contacts and structural features of domain 3.

Fedorova O, Pyle AM. Fedorova O, et al. EMBO J. 2005 Nov 16;24(22):3906-16. doi: 10.1038/sj.emboj.7600852. Epub 2005 Oct 27. EMBO J. 2005. PMID: 16252007 Free PMC article.

4

A conserved element that stabilizes the group II intron active site.

Fedorova O, Pyle AM. Fedorova O, et al. RNA. 2008 Jun;14(6):1048-56. doi: 10.1261/rna.942308. Epub 2008 Apr 25. RNA. 2008. PMID: 18441048 Free PMC article.

5

The brace for a growing scaffold: Mss116 protein promotes RNA folding by stabilizing an early assembly intermediate.

Fedorova O, Pyle AM. Fedorova O, et al. J Mol Biol. 2012 Sep 21;422(3):347-65. doi: 10.1016/j.jmb.2012.05.037. Epub 2012 Jun 13. J Mol Biol. 2012. PMID: 22705286 Free PMC article.

6

The thermodynamic basis for viral RNA detection by the RIG-I innate immune sensor.

Vela A, Fedorova O, Ding SC, Pyle AM. Vela A, et al. Among authors: fedorova o. J Biol Chem. 2012 Dec 14;287(51):42564-73. doi: 10.1074/jbc.M112.385146. Epub 2012 Oct 10. J Biol Chem. 2012. PMID: 23055530 Free PMC article.

7

Environmentally Triggerable Retinoic Acid-Inducible Gene I Agonists Using Synthetic Polymer Overhangs.

Palmer CR, Jacobson ME, Fedorova O, Pyle AM, Wilson JT. Palmer CR, et al. Among authors: fedorova o. Bioconjug Chem. 2018 Mar 21;29(3):742-747. doi: 10.1021/acs.bioconjchem.7b00697. Epub 2018 Jan 19. Bioconjug Chem. 2018. PMID: 29350913 Free PMC article.

8

A molecular beacon assay for monitoring RNA splicing.

Omran QQ, Fedorova O, Liu T, Pyle AM. Omran QQ, et al. Among authors: fedorova o. Nucleic Acids Res. 2022 Jul 22;50(13):e74. doi: 10.1093/nar/gkac242. Nucleic Acids Res. 2022. PMID: 35438748 Free PMC article.

9

Group II intron folding under near-physiological conditions: collapsing to the near-native state.

Fedorova O, Waldsich C, Pyle AM. Fedorova O, et al. J Mol Biol. 2007 Mar 2;366(4):1099-114. doi: 10.1016/j.jmb.2006.12.003. Epub 2006 Dec 6. J Mol Biol. 2007. PMID: 17196976 Free PMC article.

10

The 2'-OH group at the group II intron terminus acts as a proton shuttle.

Roitzsch M, Fedorova O, Pyle AM. Roitzsch M, et al. Among authors: fedorova o. Nat Chem Biol. 2010 Mar;6(3):218-224. doi: 10.1038/nchembio.312. Epub 2010 Jan 31. Nat Chem Biol. 2010. PMID: 20118939 Free PMC article.

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