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Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model.
Proud PC, Tsitoura D, Watson RJ, Chua BY, Aram MJ, Bewley KR, Cavell BE, Cobb R, Dowall S, Fotheringham SA, Ho CMK, Lucas V, Ngabo D, Rayner E, Ryan KA, Slack GS, Thomas S, Wand NI, Yeates P, Demaison C, Zeng W, Holmes I, Jackson DC, Bartlett NW, Mercuri F, Carroll MW. Proud PC, et al. Among authors: bartlett nw. EBioMedicine. 2021 Jan;63:103153. doi: 10.1016/j.ebiom.2020.103153. Epub 2020 Dec 3. EBioMedicine. 2021. PMID: 33279857 Free PMC article.
A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13).
Hansel TT, Tunstall T, Trujillo-Torralbo MB, Shamji B, Del-Rosario A, Dhariwal J, Kirk PDW, Stumpf MPH, Koopmann J, Telcian A, Aniscenko J, Gogsadze L, Bakhsoliani E, Stanciu L, Bartlett N, Edwards M, Walton R, Mallia P, Hunt TM, Hunt TL, Hunt DG, Westwick J, Edwards M, Kon OM, Jackson DJ, Johnston SL. Hansel TT, et al. EBioMedicine. 2017 May;19:128-138. doi: 10.1016/j.ebiom.2017.03.033. Epub 2017 Mar 28. EBioMedicine. 2017. PMID: 28373098 Free PMC article.
TLR2-mediated innate immune priming boosts lung anti-viral immunity.
Girkin J, Loo SL, Esneau C, Maltby S, Mercuri F, Chua B, Reid AT, Veerati PC, Grainge CL, Wark PAB, Knight D, Jackson D, Demaison C, Bartlett NW. Girkin J, et al. Among authors: bartlett nw. Eur Respir J. 2021 Jul 1;58(1):2001584. doi: 10.1183/13993003.01584-2020. Print 2021 Jul. Eur Respir J. 2021. PMID: 33303547 Free article.
TLR2-mediated activation of innate responses in the upper airways confers antiviral protection of the lungs.
Deliyannis G, Wong CY, McQuilten HA, Bachem A, Clarke M, Jia X, Horrocks K, Zeng W, Girkin J, Scott NE, Londrigan SL, Reading PC, Bartlett NW, Kedzierska K, Brown LE, Mercuri F, Demaison C, Jackson DC, Chua BY. Deliyannis G, et al. Among authors: bartlett nw. JCI Insight. 2021 Mar 8;6(5):e140267. doi: 10.1172/jci.insight.140267. JCI Insight. 2021. PMID: 33561017 Free PMC article.
Respiratory Viruses and Asthma.
Wark PAB, Ramsahai JM, Pathinayake P, Malik B, Bartlett NW. Wark PAB, et al. Among authors: bartlett nw. Semin Respir Crit Care Med. 2018 Feb;39(1):45-55. doi: 10.1055/s-0037-1617412. Epub 2018 Feb 10. Semin Respir Crit Care Med. 2018. PMID: 29427985 Free PMC article. Review.
Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia.
Aggarwal A, Stella AO, Walker G, Akerman A, Esneau C, Milogiannakis V, Burnett DL, McAllery S, Silva MR, Lu Y, Foster CSP, Brilot F, Pillay A, Van Hal S, Mathivanan V, Fichter C, Kindinger A, Hoppe AC, Munier ML, Amatayakul-Chantler S, Roth N, Coppola G, Symonds GP, Schofield P, Jackson J, Lenthall H, Henry JY, Mazigi O, Jäck HM, Davenport MP, Darley DR, Matthews GV, Khoury DS, Cromer D, Goodnow CC, Christ D, Robosa R, Starck DJ, Bartlett NW, Rawlinson WD, Kelleher AD, Turville SG. Aggarwal A, et al. Among authors: bartlett nw. Nat Microbiol. 2022 Jun;7(6):896-908. doi: 10.1038/s41564-022-01135-7. Epub 2022 May 30. Nat Microbiol. 2022. PMID: 35637329 Free PMC article.
91 results