Annoni A - Search Results

1

Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering.

Soldi M, Sergi Sergi L, Unali G, Kerzel T, Cuccovillo I, Capasso P, Annoni A, Biffi M, Rancoita PMV, Cantore A, Lombardo A, Naldini L, Squadrito ML, Kajaste-Rudnitski A. Soldi M, et al. Among authors: annoni a. Mol Ther Methods Clin Dev. 2020 Oct 20;19:411-425. doi: 10.1016/j.omtm.2020.10.009. eCollection 2020 Dec 11. Mol Ther Methods Clin Dev. 2020. PMID: 33294490 Free PMC article.

2

Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice.

Follenzi A, Battaglia M, Lombardo A, Annoni A, Roncarolo MG, Naldini L. Follenzi A, et al. Among authors: annoni a. Blood. 2004 May 15;103(10):3700-9. doi: 10.1182/blood-2003-09-3217. Epub 2003 Dec 30. Blood. 2004. PMID: 14701690 Free article.

3

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance.

Brown BD, Sitia G, Annoni A, Hauben E, Sergi LS, Zingale A, Roncarolo MG, Guidotti LG, Naldini L. Brown BD, et al. Among authors: annoni a. Blood. 2007 Apr 1;109(7):2797-805. doi: 10.1182/blood-2006-10-049312. Blood. 2007. PMID: 17170119 Free article.

4

The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4+CD25+ regulatory T cells.

Annoni A, Battaglia M, Follenzi A, Lombardo A, Sergi-Sergi L, Naldini L, Roncarolo MG. Annoni A, et al. Blood. 2007 Sep 15;110(6):1788-96. doi: 10.1182/blood-2006-11-059873. Epub 2007 May 10. Blood. 2007. PMID: 17495135 Free article.

5

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice.

Brown BD, Cantore A, Annoni A, Sergi LS, Lombardo A, Della Valle P, D'Angelo A, Naldini L. Brown BD, et al. Among authors: annoni a. Blood. 2007 Dec 15;110(13):4144-52. doi: 10.1182/blood-2007-03-078493. Epub 2007 Aug 28. Blood. 2007. PMID: 17726165 Free article.

6

In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance.

Annoni A, Brown BD, Cantore A, Sergi LS, Naldini L, Roncarolo MG. Annoni A, et al. Blood. 2009 Dec 10;114(25):5152-61. doi: 10.1182/blood-2009-04-214569. Blood. 2009. PMID: 19794140 Free PMC article.

7

Manipulating Immune Tolerance with Micro-RNA Regulated Gene Therapy.

Goudy KS, Annoni A, Naldini L, Roncarolo MG. Goudy KS, et al. Among authors: annoni a. Front Microbiol. 2011 Nov 14;2:221. doi: 10.3389/fmicb.2011.00221. eCollection 2011. Front Microbiol. 2011. PMID: 22144977 Free PMC article.

8

Immune responses in liver-directed lentiviral gene therapy.

Annoni A, Goudy K, Akbarpour M, Naldini L, Roncarolo MG. Annoni A, et al. Transl Res. 2013 Apr;161(4):230-40. doi: 10.1016/j.trsl.2012.12.018. Epub 2013 Jan 26. Transl Res. 2013. PMID: 23360745 Review.

9

Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice.

Annoni A, Cantore A, Della Valle P, Goudy K, Akbarpour M, Russo F, Bartolaccini S, D'Angelo A, Roncarolo MG, Naldini L. Annoni A, et al. EMBO Mol Med. 2013 Nov;5(11):1684-97. doi: 10.1002/emmm.201302857. Epub 2013 Sep 16. EMBO Mol Med. 2013. PMID: 24106222 Free PMC article.

10

Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs.

Akbarpour M, Goudy KS, Cantore A, Russo F, Sanvito F, Naldini L, Annoni A, Roncarolo MG. Akbarpour M, et al. Among authors: annoni a. Sci Transl Med. 2015 May 27;7(289):289ra81. doi: 10.1126/scitranslmed.aaa3032. Sci Transl Med. 2015. PMID: 26019217

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