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Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
Ross JL, Chen Z, Herting CJ, Grabovska Y, Szulzewsky F, Puigdelloses M, Monterroza L, Switchenko J, Wadhwani NR, Cimino PJ, Mackay A, Jones C, Read RD, MacDonald TJ, Schniederjan M, Becher OJ, Hambardzumyan D. Ross JL, et al. Among authors: cimino pj. Brain. 2021 Feb 12;144(1):53-69. doi: 10.1093/brain/awaa382. Brain. 2021. PMID: 33300045 Free PMC article.
Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma.
Wirsching HG, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino PJ, Amankulor N, Campbell JS, McFerrin L, Pattwell SS, Ene C, Hicks A, Ball M, Yan J, Zhang J, Kumasaka D, Pierce RH, Weller M, Finer M, Quéva C, Glorioso JC, Houghton AM, Holland EC. Wirsching HG, et al. Among authors: cimino pj. JCI Insight. 2019 Jul 11;4(13):e128217. doi: 10.1172/jci.insight.128217. eCollection 2019 Jul 11. JCI Insight. 2019. PMID: 31292299 Free PMC article.
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors.
Kaffes I, Szulzewsky F, Chen Z, Herting CJ, Gabanic B, Velázquez Vega JE, Shelton J, Switchenko JM, Ross JL, McSwain LF, Huse JT, Westermark B, Nelander S, Forsberg-Nilsson K, Uhrbom L, Maturi NP, Cimino PJ, Holland EC, Kettenmann H, Brennan CW, Brat DJ, Hambardzumyan D. Kaffes I, et al. Among authors: cimino pj. Oncoimmunology. 2019 Aug 22;8(11):e1655360. doi: 10.1080/2162402X.2019.1655360. eCollection 2019. Oncoimmunology. 2019. PMID: 31646100 Free PMC article.
Anti-PD-L1 antibody direct activation of macrophages contributes to a radiation-induced abscopal response in glioblastoma.
Ene CI, Kreuser SA, Jung M, Zhang H, Arora S, White Moyes K, Szulzewsky F, Barber J, Cimino PJ, Wirsching HG, Patel A, Kong P, Woodiwiss TR, Durfy SJ, Houghton AM, Pierce RH, Parney IF, Crane CA, Holland EC. Ene CI, et al. Among authors: cimino pj. Neuro Oncol. 2020 May 15;22(5):639-651. doi: 10.1093/neuonc/noz226. Neuro Oncol. 2020. PMID: 31793634 Free PMC article.
A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.
Pattwell SS, Arora S, Cimino PJ, Ozawa T, Szulzewsky F, Hoellerbauer P, Bonifert T, Hoffstrom BG, Boiani NE, Bolouri H, Correnti CE, Oldrini B, Silber JR, Squatrito M, Paddison PJ, Holland EC. Pattwell SS, et al. Among authors: cimino pj. Nat Commun. 2020 Jun 12;11(1):2977. doi: 10.1038/s41467-020-16786-5. Nat Commun. 2020. PMID: 32532995 Free PMC article.
102 results