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Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis.
Schwalm S, Beyer S, Hafizi R, Trautmann S, Geisslinger G, Adams DR, Pyne S, Pyne N, Schaefer L, Huwiler A, Pfeilschifter J. Schwalm S, et al. Among authors: pyne n, pyne s. Cell Signal. 2021 Mar;79:109881. doi: 10.1016/j.cellsig.2020.109881. Epub 2020 Dec 8. Cell Signal. 2021. PMID: 33301900 Free article.
Sphingosine 1-phosphate and cancer.
Pyne NJ, El Buri A, Adams DR, Pyne S. Pyne NJ, et al. Adv Biol Regul. 2018 May;68:97-106. doi: 10.1016/j.jbior.2017.09.006. Epub 2017 Sep 15. Adv Biol Regul. 2018. PMID: 28942351 Free article. Review.
Sphingosine Kinases as Druggable Targets.
Pyne S, Adams DR, Pyne NJ. Pyne S, et al. Handb Exp Pharmacol. 2020;259:49-76. doi: 10.1007/164_2018_96. Handb Exp Pharmacol. 2020. PMID: 29460151 Free article.
214 results