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Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis.
Schwalm S, Beyer S, Hafizi R, Trautmann S, Geisslinger G, Adams DR, Pyne S, Pyne N, Schaefer L, Huwiler A, Pfeilschifter J. Schwalm S, et al. Among authors: schaefer l. Cell Signal. 2021 Mar;79:109881. doi: 10.1016/j.cellsig.2020.109881. Epub 2020 Dec 8. Cell Signal. 2021. PMID: 33301900 Free article.
CXCL16 and oxLDL are induced in the onset of diabetic nephropathy.
Gutwein P, Abdel-Bakky MS, Doberstein K, Schramme A, Beckmann J, Schaefer L, Amann K, Doller A, Kämpfer-Kolb N, Abdel-Aziz AA, El Sayed el SM, Pfeilschifter J. Gutwein P, et al. Among authors: schaefer l. J Cell Mol Med. 2009 Sep;13(9B):3809-25. doi: 10.1111/j.1582-4934.2009.00761.x. Epub 2009 May 1. J Cell Mol Med. 2009. PMID: 19426159 Free PMC article.
Nitric oxide inhibits glomerular TGF-beta signaling via SMOC-1.
Dreieicher E, Beck KF, Lazaroski S, Boosen M, Tsalastra-Greul W, Beck M, Fleming I, Schaefer L, Pfeilschifter J. Dreieicher E, et al. Among authors: schaefer l. J Am Soc Nephrol. 2009 Sep;20(9):1963-74. doi: 10.1681/ASN.2008060653. Epub 2009 Jul 2. J Am Soc Nephrol. 2009. PMID: 19578009 Free PMC article.
655 results