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Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells.
Nat Commun. 2020 Dec 10;11(1):6335. doi: 10.1038/s41467-020-20138-8.
Nat Commun. 2020.
PMID: 33303745
Free PMC article.
Inhibition of RANK signaling as a potential immunotherapy in breast cancer.
Gómez-Aleza C, González-Suárez E.
Gómez-Aleza C, et al.
Oncoimmunology. 2021 May 14;10(1):1923156. doi: 10.1080/2162402X.2021.1923156.
Oncoimmunology. 2021.
PMID: 34026334
Free PMC article.
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RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness.
Benítez S, Cordero A, Santamaría PG, Redondo-Pedraza J, Rocha AS, Collado-Solé A, Jimenez M, Sanz-Moreno A, Yoldi G, Santos JC, De Benedictis I, Gómez-Aleza C, Da Silva-Álvarez S, Troulé K, Gómez-López G, Alcazar N, Palmero I, Collado M, Serrano M, Gonzalez-Suarez E.
Benítez S, et al. Among authors: gomez aleza c.
Dev Cell. 2021 Jun 21;56(12):1727-1741.e7. doi: 10.1016/j.devcel.2021.04.022. Epub 2021 May 17.
Dev Cell. 2021.
PMID: 34004159
Free PMC article.
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RANK is a poor prognosis marker and a therapeutic target in ER-negative postmenopausal breast cancer.
Ciscar M, Trinidad EM, Perez-Chacon G, Alsaleem M, Jimenez M, Jimenez-Santos MJ, Perez-Montoyo H, Sanz-Moreno A, Vethencourt A, Toss M, Petit A, Soler-Monso MT, Lopez V, Gomez-Miragaya J, Gomez-Aleza C, Dobrolecki LE, Lewis MT, Bruna A, Mouron S, Quintela-Fandino M, Al-Shahrour F, Martinez-Aranda A, Sierra A, Green AR, Rakha E, Gonzalez-Suarez E.
Ciscar M, et al. Among authors: gomez aleza c.
EMBO Mol Med. 2023 Apr 11;15(4):e16715. doi: 10.15252/emmm.202216715. Epub 2023 Mar 7.
EMBO Mol Med. 2023.
PMID: 36880458
Free PMC article.
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