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Cellular Biology of Tau Diversity and Pathogenic Conformers.
Kang SG, Eskandari-Sedighi G, Hromadkova L, Safar JG, Westaway D. Kang SG, et al. Among authors: safar jg. Front Neurol. 2020 Nov 12;11:590199. doi: 10.3389/fneur.2020.590199. eCollection 2020. Front Neurol. 2020. PMID: 33304310 Free PMC article. Review.
Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation.
Lau A, McDonald A, Daude N, Mays CE, Walter ED, Aglietti R, Mercer RC, Wohlgemuth S, van der Merwe J, Yang J, Gapeshina H, Kim C, Grams J, Shi B, Wille H, Balachandran A, Schmitt-Ulms G, Safar JG, Millhauser GL, Westaway D. Lau A, et al. Among authors: safar jg. EMBO Mol Med. 2015 Mar;7(3):339-56. doi: 10.15252/emmm.201404588. EMBO Mol Med. 2015. PMID: 25661904 Free PMC article.
A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.
Mercer RCC, Daude N, Dorosh L, Fu ZL, Mays CE, Gapeshina H, Wohlgemuth SL, Acevedo-Morantes CY, Yang J, Cashman NR, Coulthart MB, Pearson DM, Joseph JT, Wille H, Safar JG, Jansen GH, Stepanova M, Sykes BD, Westaway D. Mercer RCC, et al. Among authors: safar jg. PLoS Pathog. 2018 Jan 16;14(1):e1006826. doi: 10.1371/journal.ppat.1006826. eCollection 2018 Jan. PLoS Pathog. 2018. PMID: 29338055 Free PMC article.
Diverse, evolving conformer populations drive distinct phenotypes in frontotemporal lobar degeneration caused by the same MAPT-P301L mutation.
Daude N, Kim C, Kang SG, Eskandari-Sedighi G, Haldiman T, Yang J, Fleck SC, Gomez-Cardona E, Han ZZ, Borrego-Ecija S, Wohlgemuth S, Julien O, Wille H, Molina-Porcel L, Gelpi E, Safar JG, Westaway D. Daude N, et al. Among authors: safar jg. Acta Neuropathol. 2020 Jun;139(6):1045-1070. doi: 10.1007/s00401-020-02148-4. Epub 2020 Mar 26. Acta Neuropathol. 2020. PMID: 32219515 Free PMC article.
Correction to: Diverse, evolving conformer populations drive distinct phenotypes in frontotemporal lobar degeneration caused by the same MAPT‑P301L mutation.
Daude N, Kim C, Kang SG, Eskandari-Sedighi G, Haldiman T, Yang J, Fleck SC, Gomez-Cardona E, Han ZZ, Borrego-Ecija S, Wohlgemuth S, Julien O, Wille H, Molina-Porcel L, Gelpi E, Safar JG, Westaway D. Daude N, et al. Among authors: safar jg. Acta Neuropathol. 2021 Mar;141(3):467-468. doi: 10.1007/s00401-021-02262-x. Acta Neuropathol. 2021. PMID: 33515276 Free PMC article. No abstract available.
120 results