Wenthe J - Search Results

1

Intratumoral immunostimulatory AdCD40L gene therapy in patients with advanced solid tumors.

Irenaeus S, Hellström V, Wenthe J, Krause J, Sundin A, Ahlström H, Tufveson G, Tötterman TH, Loskog A, Ullenhag GJ. Irenaeus S, et al. Among authors: wenthe j. Cancer Gene Ther. 2021 Nov;28(10-11):1188-1197. doi: 10.1038/s41417-020-00271-8. Epub 2020 Dec 14. Cancer Gene Ther. 2021. PMID: 33318679

2

Local irradiation does not enhance the effect of immunostimulatory AdCD40L gene therapy combined with low dose cyclophosphamide in melanoma patients.

Irenaeus S, Schiza A, Mangsbo SM, Wenthe J, Eriksson E, Krause J, Sundin A, Ahlström H, Tötterman TH, Loskog A, Ullenhag GJ. Irenaeus S, et al. Among authors: wenthe j. Oncotarget. 2017 Jul 31;8(45):78573-78587. doi: 10.18632/oncotarget.19750. eCollection 2017 Oct 3. Oncotarget. 2017. PMID: 29108250 Free PMC article.

3

Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients.

Schiza A, Wenthe J, Mangsbo S, Eriksson E, Nilsson A, Tötterman TH, Loskog A, Ullenhag G. Schiza A, et al. Among authors: wenthe j. J Transl Med. 2017 Apr 20;15(1):79. doi: 10.1186/s12967-017-1182-z. J Transl Med. 2017. PMID: 28427434 Free PMC article. Clinical Trial.

4

Gemcitabine reduces MDSCs, tregs and TGFβ-1 while restoring the teff/treg ratio in patients with pancreatic cancer.

Eriksson E, Wenthe J, Irenaeus S, Loskog A, Ullenhag G. Eriksson E, et al. Among authors: wenthe j. J Transl Med. 2016 Sep 29;14(1):282. doi: 10.1186/s12967-016-1037-z. J Transl Med. 2016. PMID: 27687804 Free PMC article.

5

Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40.

Wenthe J, Naseri S, Hellström AC, Wiklund HJ, Eriksson E, Loskog A. Wenthe J, et al. Cancer Gene Ther. 2020 Dec;27(12):948-959. doi: 10.1038/s41417-020-0176-9. Epub 2020 May 1. Cancer Gene Ther. 2020. PMID: 32355275 Free PMC article.

6

Immune priming using DC- and T cell-targeting gene therapy sensitizes both treated and distant B16 tumors to checkpoint inhibition.

Wenthe J, Naseri S, Hellström AC, Moreno R, Ullenhag G, Alemany R, Lövgren T, Eriksson E, Loskog A. Wenthe J, et al. Mol Ther Oncolytics. 2022 Jan 10;24:429-442. doi: 10.1016/j.omto.2022.01.003. eCollection 2022 Mar 17. Mol Ther Oncolytics. 2022. PMID: 35141399 Free PMC article.

7

Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus.

Eriksson E, Milenova I, Wenthe J, Ståhle M, Leja-Jarblad J, Ullenhag G, Dimberg A, Moreno R, Alemany R, Loskog A. Eriksson E, et al. Among authors: wenthe j. Clin Cancer Res. 2017 Oct 1;23(19):5846-5857. doi: 10.1158/1078-0432.CCR-17-0285. Epub 2017 May 23. Clin Cancer Res. 2017. PMID: 28536305

8

IL-6 Signaling Blockade during CD40-Mediated Immune Activation Favors Antitumor Factors by Reducing TGF-β, Collagen Type I, and PD-L1/PD-1.

Eriksson E, Milenova I, Wenthe J, Moreno R, Alemany R, Loskog A. Eriksson E, et al. Among authors: wenthe j. J Immunol. 2019 Feb 1;202(3):787-798. doi: 10.4049/jimmunol.1800717. Epub 2019 Jan 7. J Immunol. 2019. PMID: 30617223

9

Systemic immunity upon local oncolytic virotherapy armed with immunostimulatory genes may be supported by tumor-derived exosomes.

Labani-Motlagh A, Naseri S, Wenthe J, Eriksson E, Loskog A. Labani-Motlagh A, et al. Among authors: wenthe j. Mol Ther Oncolytics. 2021 Feb 17;20:508-518. doi: 10.1016/j.omto.2021.02.007. eCollection 2021 Mar 26. Mol Ther Oncolytics. 2021. PMID: 33738337 Free PMC article.

10

A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia.

Enblad G, Karlsson H, Gammelgård G, Wenthe J, Lövgren T, Amini RM, Wikstrom KI, Essand M, Savoldo B, Hallböök H, Höglund M, Dotti G, Brenner MK, Hagberg H, Loskog A. Enblad G, et al. Among authors: wenthe j. Clin Cancer Res. 2018 Dec 15;24(24):6185-6194. doi: 10.1158/1078-0432.CCR-18-0426. Epub 2018 Aug 10. Clin Cancer Res. 2018. PMID: 30097433 Clinical Trial.

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