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Reconstitution of the oocyte transcriptional network with transcription factors.
Hamazaki N, Kyogoku H, Araki H, Miura F, Horikawa C, Hamada N, Shimamoto S, Hikabe O, Nakashima K, Kitajima TS, Ito T, Leitch HG, Hayashi K. Hamazaki N, et al. Among authors: leitch hg. Nature. 2021 Jan;589(7841):264-269. doi: 10.1038/s41586-020-3027-9. Epub 2020 Dec 16. Nature. 2021. PMID: 33328630
Naive pluripotency is associated with global DNA hypomethylation.
Leitch HG, McEwen KR, Turp A, Encheva V, Carroll T, Grabole N, Mansfield W, Nashun B, Knezovich JG, Smith A, Surani MA, Hajkova P. Leitch HG, et al. Nat Struct Mol Biol. 2013 Mar;20(3):311-6. doi: 10.1038/nsmb.2510. Epub 2013 Feb 17. Nat Struct Mol Biol. 2013. PMID: 23416945 Free PMC article.
Hallmarks of pluripotency.
De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, Park PJ, Daley GQ. De Los Angeles A, et al. Among authors: leitch hg. Nature. 2015 Sep 24;525(7570):469-78. doi: 10.1038/nature15515. Nature. 2015. PMID: 26399828 Review.
Eggs sense high-fat diet.
Leitch HG, Hajkova P. Leitch HG, et al. Nat Genet. 2018 Mar;50(3):318-319. doi: 10.1038/s41588-018-0068-1. Nat Genet. 2018. PMID: 29511285 Free article. No abstract available.
Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte.
Hill PWS, Leitch HG, Requena CE, Sun Z, Amouroux R, Roman-Trufero M, Borkowska M, Terragni J, Vaisvila R, Linnett S, Bagci H, Dharmalingham G, Haberle V, Lenhard B, Zheng Y, Pradhan S, Hajkova P. Hill PWS, et al. Among authors: leitch hg. Nature. 2018 Mar 15;555(7696):392-396. doi: 10.1038/nature25964. Epub 2018 Mar 7. Nature. 2018. PMID: 29513657 Free PMC article.
Determining the potency of primordial germ cells by injection into early mouse embryos.
Sepulveda-Rincon LP, Wang YF, Whilding C, Moyon B, Ojarikre OA, Maciulyte V, Hamazaki N, Hayashi K, Turner JMA, Leitch HG. Sepulveda-Rincon LP, et al. Among authors: leitch hg. Dev Cell. 2024 Mar 25;59(6):695-704.e5. doi: 10.1016/j.devcel.2024.01.022. Epub 2024 Feb 14. Dev Cell. 2024. PMID: 38359835 Free article.
37 results