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Post-acute COVID-19 associated with evidence of bystander T-cell activation and a recurring antibiotic-resistant bacterial pneumonia.
Gregorova M, Morse D, Brignoli T, Steventon J, Hamilton F, Albur M, Arnold D, Thomas M, Halliday A, Baum H, Rice C, Avison MB, Davidson AD, Santopaolo M, Oliver E, Goenka A, Finn A, Wooldridge L, Amulic B, Boyton RJ, Altmann DM, Butler DK, McMurray C, Stockton J, Nicholls S, Cooper C, Loman N, Cox MJ, Rivino L, Massey RC. Gregorova M, et al. Among authors: wooldridge l. Elife. 2020 Dec 17;9:e63430. doi: 10.7554/eLife.63430. Elife. 2020. PMID: 33331820 Free PMC article.
Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2.
Goenka A, Halliday A, Gregorova M, Milodowski E, Thomas A, Williamson MK, Baum H, Oliver E, Long AE, Knezevic L, Williams AJK, Lampasona V, Piemonti L, Gupta K, Di Bartolo N, Berger I, Toye AM, Vipond B, Muir P, Bernatoniene J, Bailey M, Gillespie KM, Davidson AD, Wooldridge L, Rivino L, Finn A. Goenka A, et al. Among authors: wooldridge l. Cell Rep Med. 2021 Jul 20;2(7):100327. doi: 10.1016/j.xcrm.2021.100327. Epub 2021 Jun 9. Cell Rep Med. 2021. PMID: 34124701 Free PMC article.
Ready and waiting to go.
Rivino L, Wooldridge L. Rivino L, et al. Among authors: wooldridge l. Elife. 2023 Jan 6;12:e85080. doi: 10.7554/eLife.85080. Elife. 2023. PMID: 36607230 Free PMC article.
Prolonged T-cell activation and long COVID symptoms independently associate with severe COVID-19 at 3 months.
Santopaolo M, Gregorova M, Hamilton F, Arnold D, Long A, Lacey A, Oliver E, Halliday A, Baum H, Hamilton K, Milligan R, Pearce O, Knezevic L, Morales Aza B, Milne A, Milodowski E, Jones E, Lazarus R, Goenka A, Finn A, Maskell N, Davidson AD, Gillespie K, Wooldridge L, Rivino L. Santopaolo M, et al. Among authors: wooldridge l. Elife. 2023 Jun 13;12:e85009. doi: 10.7554/eLife.85009. Elife. 2023. PMID: 37310006 Free PMC article.
Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
Man S, Redman JE, Cross DL, Cole DK, Can I, Davies B, Hashimdeen SS, Reid R, Llewellyn-Lacey S, Miners KL, Ladell K, Lissina A, Brown PE, Wooldridge L, Price DA, Rizkallah PJ. Man S, et al. Among authors: wooldridge l. J Immunol. 2021 Aug 15;207(4):1009-1017. doi: 10.4049/jimmunol.2000756. Epub 2021 Jul 28. J Immunol. 2021. PMID: 34321228 Free PMC article.
CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.
Dockree T, Holland CJ, Clement M, Ladell K, McLaren JE, van den Berg HA, Gostick E, L Miners K, Llewellyn-Lacey S, Bridgeman JS, Man S, Bailey M, Burrows SR, Price DA, Wooldridge L. Dockree T, et al. Among authors: l miners k, wooldridge l. Immunol Cell Biol. 2017 Jan;95(1):68-76. doi: 10.1038/icb.2016.85. Epub 2016 Nov 8. Immunol Cell Biol. 2017. PMID: 27670790 Free PMC article.
GPU-Accelerated Discovery of Pathogen-Derived Molecular Mimics of a T-Cell Insulin Epitope.
Whalley T, Dolton G, Brown PE, Wall A, Wooldridge L, van den Berg H, Fuller A, Hopkins JR, Crowther MD, Attaf M, Knight RR, Cole DK, Peakman M, Sewell AK, Szomolay B. Whalley T, et al. Among authors: wooldridge l. Front Immunol. 2020 Feb 28;11:296. doi: 10.3389/fimmu.2020.00296. eCollection 2020. Front Immunol. 2020. PMID: 32184781 Free PMC article.
CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor.
Clement M, Knezevic L, Dockree T, McLaren JE, Ladell K, Miners KL, Llewellyn-Lacey S, Rubina A, Francis O, Cole DK, Sewell AK, Bridgeman JS, Price DA, van den Berg HA, Wooldridge L. Clement M, et al. Among authors: wooldridge l. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2019639118. doi: 10.1073/pnas.2019639118. Proc Natl Acad Sci U S A. 2021. PMID: 34272276 Free PMC article.
Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics.
Neller MA, Ladell K, McLaren JE, Matthews KK, Gostick E, Pentier JM, Dolton G, Schauenburg AJ, Koning D, Fontaine Costa AI, Watkins TS, Venturi V, Smith C, Khanna R, Miners K, Clement M, Wooldridge L, Cole DK, van Baarle D, Sewell AK, Burrows SR, Price DA, Miles JJ. Neller MA, et al. Among authors: wooldridge l. Immunol Cell Biol. 2015 Aug;93(7):625-33. doi: 10.1038/icb.2015.17. Epub 2015 Mar 24. Immunol Cell Biol. 2015. PMID: 25801351 Free PMC article.
High avidity antigen-specific CTL identified by CD8-independent tetramer staining.
Choi EM, Chen JL, Wooldridge L, Salio M, Lissina A, Lissin N, Hermans IF, Silk JD, Mirza F, Palmowski MJ, Dunbar PR, Jakobsen BK, Sewell AK, Cerundolo V. Choi EM, et al. Among authors: wooldridge l. J Immunol. 2003 Nov 15;171(10):5116-23. doi: 10.4049/jimmunol.171.10.5116. J Immunol. 2003. PMID: 14607910
112 results