Liu L - Search Results

1

Berberine diminishes cancer cell PD-L1 expression and facilitates antitumor immunity via inhibiting the deubiquitination activity of CSN5.

Liu Y, Liu X, Zhang N, Yin M, Dong J, Zeng Q, Mao G, Song D, Liu L, Deng H. Liu Y, et al. Among authors: liu x, liu l. Acta Pharm Sin B. 2020 Dec;10(12):2299-2312. doi: 10.1016/j.apsb.2020.06.014. Epub 2020 Jun 30. Acta Pharm Sin B. 2020. PMID: 33354502 Free PMC article.

2

Tubeimoside-1 induces TFEB-dependent lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting mTOR.

Liu X, Yin M, Dong J, Mao G, Min W, Kuang Z, Yang P, Liu L, Zhang N, Deng H. Liu X, et al. Among authors: liu l. Acta Pharm Sin B. 2021 Oct;11(10):3134-3149. doi: 10.1016/j.apsb.2021.03.039. Epub 2021 Apr 1. Acta Pharm Sin B. 2021. PMID: 34745852 Free PMC article.

3

Glycogen synthase kinase-3β antagonizes ROS-induced hepatocellular carcinoma cell death through suppression of the apoptosis signal-regulating kinase 1.

Zhang N, Liu L, Dou Y, Song D, Deng H. Zhang N, et al. Among authors: liu l. Med Oncol. 2016 Jul;33(7):60. doi: 10.1007/s12032-016-0776-2. Epub 2016 May 24. Med Oncol. 2016. PMID: 27221474

4

Lysosomal dysfunction and autophagy blockade contribute to IMB-6G-induced apoptosis in pancreatic cancer cells.

Liu L, Zhang N, Dou Y, Mao G, Bi C, Pang W, Liu X, Song D, Deng H. Liu L, et al. Among authors: liu x. Sci Rep. 2017 Jan 31;7:41862. doi: 10.1038/srep41862. Sci Rep. 2017. PMID: 28139733 Free PMC article.

5

Synthesis and Identification of Novel Berberine Derivatives as Potent Inhibitors against TNF-α-Induced NF-κB Activation.

Wang YX, Liu L, Zeng QX, Fan TY, Jiang JD, Deng HB, Song DQ. Wang YX, et al. Among authors: liu l. Molecules. 2017 Jul 27;22(8):1257. doi: 10.3390/molecules22081257. Molecules. 2017. PMID: 28749438 Free PMC article.

6

MPB, a novel berberine derivative, enhances lysosomal and bactericidal properties via TGF-β-activated kinase 1-dependent activation of the transcription factor EB.

Liu X, Zhang N, Liu Y, Liu L, Zeng Q, Yin M, Wang Y, Song D, Deng H. Liu X, et al. Among authors: liu y, liu l. FASEB J. 2019 Jan;33(1):1468-1481. doi: 10.1096/fj.201801198R. Epub 2018 Aug 30. FASEB J. 2019. PMID: 30161000

Therefore, our study reveals a novel mechanism by which MPB controls JNK and AMPK phosphorylation cascades to activate lysosomal function and bactericidal activity via TAK1 K158-dependent manner, which may offer insight into novel therapeutic strategies to control bacterial infec …

Therefore, our study reveals a novel mechanism by which MPB controls JNK and AMPK phosphorylation cascades to activate lysosomal function an …

7

Resibufogenin suppresses transforming growth factor-β-activated kinase 1-mediated nuclear factor-κB activity through protein kinase C-dependent inhibition of glycogen synthase kinase 3.

Liu L, Liu Y, Liu X, Zhang N, Mao G, Zeng Q, Yin M, Song D, Deng H. Liu L, et al. Among authors: liu y, liu x. Cancer Sci. 2018 Nov;109(11):3611-3622. doi: 10.1111/cas.13788. Epub 2018 Sep 23. Cancer Sci. 2018. PMID: 30168902 Free PMC article.

8

SA-49, a novel aloperine derivative, induces MITF-dependent lysosomal degradation of PD-L1.

Zhang N, Dou Y, Liu L, Zhang X, Liu X, Zeng Q, Liu Y, Yin M, Liu X, Deng H, Song D. Zhang N, et al. Among authors: liu y, liu x, liu l. EBioMedicine. 2019 Feb;40:151-162. doi: 10.1016/j.ebiom.2019.01.054. Epub 2019 Jan 31. EBioMedicine. 2019. PMID: 30711516 Free PMC article.

9

IMB-6G, a novel N-substituted sophoridinic acid derivative, induces endoplasmic reticulum stress-mediated apoptosis via activation of IRE1α and PERK signaling.

Zhang N, Bi C, Liu L, Dou Y, Tang S, Pang W, Deng H, Song D. Zhang N, et al. Among authors: liu l. Oncotarget. 2016 Apr 26;7(17):23860-73. doi: 10.18632/oncotarget.8184. Oncotarget. 2016. PMID: 27009865 Free PMC article.

10

Glycogen synthase kinase-3β inhibition promotes lysosome-dependent degradation of c-FLIP_L in hepatocellular carcinoma.

Zhang N, Liu X, Liu L, Deng Z, Zeng Q, Pang W, Liu Y, Song D, Deng H. Zhang N, et al. Among authors: liu y, liu x, liu l. Cell Death Dis. 2018 Feb 14;9(2):230. doi: 10.1038/s41419-018-0309-3. Cell Death Dis. 2018. PMID: 29445085 Free PMC article.

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