Arafeh R - Search Results

1

MEK Inhibition Reverses Aberrant Signaling in Melanoma Cells through Reorganization of NRas and BRAF in Self Nanoclusters.

Yakovian O, Sajman J, Arafeh R, Neve-Oz Y, Alon M, Samuels Y, Sherman E. Yakovian O, et al. Among authors: arafeh r. Cancer Res. 2021 Mar 1;81(5):1279-1292. doi: 10.1158/0008-5472.CAN-20-1205. Epub 2020 Dec 21. Cancer Res. 2021. PMID: 33355187 Free PMC article.

2

Recurrent inactivating RASA2 mutations in melanoma.

Arafeh R, Qutob N, Emmanuel R, Keren-Paz A, Madore J, Elkahloun A, Wilmott JS, Gartner JJ, Di Pizio A, Winograd-Katz S, Sindiri S, Rotkopf R, Dutton-Regester K, Johansson P, Pritchard AL, Waddell N, Hill VK, Lin JC, Hevroni Y, Rosenberg SA, Khan J, Ben-Dor S, Niv MY, Ulitsky I, Mann GJ, Scolyer RA, Hayward NK, Samuels Y. Arafeh R, et al. Nat Genet. 2015 Dec;47(12):1408-10. doi: 10.1038/ng.3427. Epub 2015 Oct 26. Nat Genet. 2015. PMID: 26502337 Free PMC article.

3

Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.

Arafeh R, Flores K, Keren-Paz A, Maik-Rachline G, Gutkind N, Rosenberg S, Seger R, Samuels Y. Arafeh R, et al. Sci Rep. 2017 Nov 27;7(1):16345. doi: 10.1038/s41598-017-16558-0. Sci Rep. 2017. PMID: 29180761 Free PMC article.

4

Harnessing synthetic lethality to predict the response to cancer treatment.

Lee JS, Das A, Jerby-Arnon L, Arafeh R, Auslander N, Davidson M, McGarry L, James D, Amzallag A, Park SG, Cheng K, Robinson W, Atias D, Stossel C, Buzhor E, Stein G, Waterfall JJ, Meltzer PS, Golan T, Hannenhalli S, Gottlieb E, Benes CH, Samuels Y, Shanks E, Ruppin E. Lee JS, et al. Among authors: arafeh r. Nat Commun. 2018 Jun 29;9(1):2546. doi: 10.1038/s41467-018-04647-1. Nat Commun. 2018. PMID: 29959327 Free PMC article.

5

CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma.

Alon M, Arafeh R, Lee JS, Madan S, Kalaora S, Nagler A, Abgarian T, Greenberg P, Ruppin E, Samuels Y. Alon M, et al. Among authors: arafeh r. Oncotarget. 2018 Jul 27;9(58):31264-31277. doi: 10.18632/oncotarget.25805. eCollection 2018 Jul 27. Oncotarget. 2018. PMID: 30131853 Free PMC article.

6

RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma.

Arafeh R, Di Pizio A, Elkahloun AG, Dym O, Niv MY, Samuels Y. Arafeh R, et al. Oncogene. 2019 Mar;38(13):2432-2434. doi: 10.1038/s41388-018-0578-4. Epub 2018 Nov 26. Oncogene. 2019. PMID: 30478445 No abstract available.

7

PIK3CA in cancer: The past 30 years.

Arafeh R, Samuels Y. Arafeh R, et al. Semin Cancer Biol. 2019 Dec;59:36-49. doi: 10.1016/j.semcancer.2019.02.002. Epub 2019 Feb 10. Semin Cancer Biol. 2019. PMID: 30742905 Review.

8

Author Correction: Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.

Arafeh R, Flores K, Keren-Paz A, Maik-Rachline G, Gutkind N, Rosenberg S, Seger R, Samuels Y. Arafeh R, et al. Sci Rep. 2019 Mar 12;9(1):4672. doi: 10.1038/s41598-018-37931-7. Sci Rep. 2019. PMID: 30858388 Free PMC article.

9

Correction: CAPN1 is a novel binding partner and regulator of the tumor suppressor NF1 in melanoma.

Alon M, Arafeh R, Lee JS, Madan S, Kalaora S, Nagler A, Abgarian T, Greenberg P, Ruppin E, Samuels Y. Alon M, et al. Among authors: arafeh r. Oncotarget. 2019 Feb 12;10(13):1344. doi: 10.18632/oncotarget.26685. eCollection 2019 Feb 12. Oncotarget. 2019. PMID: 30863494 Free PMC article.

10

A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma.

Nagler A, Vredevoogd DW, Alon M, Cheng PF, Trabish S, Kalaora S, Arafeh R, Goldin V, Levesque MP, Peeper DS, Samuels Y. Nagler A, et al. Among authors: arafeh r. Pigment Cell Melanoma Res. 2020 Mar;33(2):334-344. doi: 10.1111/pcmr.12825. Epub 2019 Oct 10. Pigment Cell Melanoma Res. 2020. PMID: 31549767 Free PMC article.

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