Unger A - Search Results

1

Graded titin cleavage progressively reduces tension and uncovers the source of A-band stability in contracting muscle.

Li Y, Hessel AL, Unger A, Ing D, Recker J, Koser F, Freundt JK, Linke WA. Li Y, et al. Among authors: unger a. Elife. 2020 Dec 24;9:e64107. doi: 10.7554/eLife.64107. Elife. 2020. PMID: 33357376 Free PMC article.

2

Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin.

Swist S, Unger A, Li Y, Vöge A, von Frieling-Salewsky M, Skärlén Å, Cacciani N, Braun T, Larsson L, Linke WA. Swist S, et al. Among authors: unger a. Nat Commun. 2020 Sep 8;11(1):4479. doi: 10.1038/s41467-020-18131-2. Nat Commun. 2020. PMID: 32900999 Free PMC article.

3

Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function.

Voelkel T, Andresen C, Unger A, Just S, Rottbauer W, Linke WA. Voelkel T, et al. Among authors: unger a. Biochim Biophys Acta. 2013 Apr;1833(4):812-22. doi: 10.1016/j.bbamcr.2012.09.012. Epub 2012 Oct 6. Biochim Biophys Acta. 2013. PMID: 23047121 Free article.

4

Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins.

Kötter S, Unger A, Hamdani N, Lang P, Vorgerd M, Nagel-Steger L, Linke WA. Kötter S, et al. Among authors: unger a. J Cell Biol. 2014 Jan 20;204(2):187-202. doi: 10.1083/jcb.201306077. Epub 2014 Jan 13. J Cell Biol. 2014. PMID: 24421331 Free PMC article.

5

Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function.

Unger A, Beckendorf L, Böhme P, Kley R, von Frieling-Salewsky M, Lochmüller H, Schröder R, Fürst DO, Vorgerd M, Linke WA. Unger A, et al. Acta Neuropathol Commun. 2017 Sep 15;5(1):72. doi: 10.1186/s40478-017-0474-0. Acta Neuropathol Commun. 2017. PMID: 28915917 Free PMC article.

6

Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx).

Loescher CM, Breitkreuz M, Li Y, Nickel A, Unger A, Dietl A, Schmidt A, Mohamed BA, Kötter S, Schmitt JP, Krüger M, Krüger M, Toischer K, Maack C, Leichert LI, Hamdani N, Linke WA. Loescher CM, et al. Among authors: unger a. Proc Natl Acad Sci U S A. 2020 Sep 29;117(39):24545-24556. doi: 10.1073/pnas.2004900117. Epub 2020 Sep 14. Proc Natl Acad Sci U S A. 2020. PMID: 32929035 Free PMC article.

7

A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues.

Rivas-Pardo JA, Li Y, Mártonfalvi Z, Tapia-Rojo R, Unger A, Fernández-Trasancos Á, Herrero-Galán E, Velázquez-Carreras D, Fernández JM, Linke WA, Alegre-Cebollada J. Rivas-Pardo JA, et al. Among authors: unger a. Nat Commun. 2020 Apr 28;11(1):2060. doi: 10.1038/s41467-020-15465-9. Nat Commun. 2020. PMID: 32345978 Free PMC article.

8

Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes.

Krysiak J, Unger A, Beckendorf L, Hamdani N, von Frieling-Salewsky M, Redfield MM, Dos Remedios CG, Sheikh F, Gergs U, Boknik P, Linke WA. Krysiak J, et al. Among authors: unger a. Nat Commun. 2018 Jan 17;9(1):262. doi: 10.1038/s41467-017-02483-3. Nat Commun. 2018. PMID: 29343782 Free PMC article.

9

A novel isoform of myosin 18A (Myo18Aγ) is an essential sarcomeric protein in mouse heart.

Horsthemke M, Nutter LMJ, Bachg AC, Skryabin BV, Honnert U, Zobel T, Bogdan S, Stoll M, Seidl MD, Müller FU, Ravens U, Unger A, Linke WA, van Gorp PRR, de Vries AAF, Bähler M, Hanley PJ. Horsthemke M, et al. Among authors: unger a. J Biol Chem. 2019 May 3;294(18):7202-7218. doi: 10.1074/jbc.RA118.004560. Epub 2019 Feb 8. J Biol Chem. 2019. PMID: 30737279 Free PMC article.

10

Imbalances in protein homeostasis caused by mutant desmin.

Winter L, Unger A, Berwanger C, Spörrer M, Türk M, Chevessier F, Strucksberg KH, Schlötzer-Schrehardt U, Wittig I, Goldmann WH, Marcus K, Linke WA, Clemen CS, Schröder R. Winter L, et al. Among authors: unger a. Neuropathol Appl Neurobiol. 2019 Aug;45(5):476-494. doi: 10.1111/nan.12516. Epub 2018 Sep 26. Neuropathol Appl Neurobiol. 2019. PMID: 30179276

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