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Page 1
Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment.
Carbó JM, León TE, Font-Díaz J, De la Rosa JV, Castrillo A, Picard FR, Staudenraus D, Huber M, Cedó L, Escolà-Gil JC, Campos L, Bakiri L, Wagner EF, Caelles C, Stratmann T, Van Ginderachter JA, Valledor AF. Carbó JM, et al. Among authors: castrillo a. Cancer Res. 2021 Feb 15;81(4):968-985. doi: 10.1158/0008-5472.CAN-19-3360. Epub 2020 Dec 23. Cancer Res. 2021. PMID: 33361391 Free article.
Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.
A-Gonzalez N, Bensinger SJ, Hong C, Beceiro S, Bradley MN, Zelcer N, Deniz J, Ramirez C, Díaz M, Gallardo G, de Galarreta CR, Salazar J, Lopez F, Edwards P, Parks J, Andujar M, Tontonoz P, Castrillo A. A-Gonzalez N, et al. Among authors: castrillo a. Immunity. 2009 Aug 21;31(2):245-58. doi: 10.1016/j.immuni.2009.06.018. Epub 2009 Jul 30. Immunity. 2009. PMID: 19646905 Free PMC article.
The nuclear receptor LXRα controls the functional specialization of splenic macrophages.
A-Gonzalez N, Guillen JA, Gallardo G, Diaz M, de la Rosa JV, Hernandez IH, Casanova-Acebes M, Lopez F, Tabraue C, Beceiro S, Hong C, Lara PC, Andujar M, Arai S, Miyazaki T, Li S, Corbi AL, Tontonoz P, Hidalgo A, Castrillo A. A-Gonzalez N, et al. Among authors: castrillo a. Nat Immunol. 2013 Aug;14(8):831-9. doi: 10.1038/ni.2622. Epub 2013 Jun 16. Nat Immunol. 2013. PMID: 23770640 Free PMC article.
The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.
Matalonga J, Glaria E, Bresque M, Escande C, Carbó JM, Kiefer K, Vicente R, León TE, Beceiro S, Pascual-García M, Serret J, Sanjurjo L, Morón-Ros S, Riera A, Paytubi S, Juarez A, Sotillo F, Lindbom L, Caelles C, Sarrias MR, Sancho J, Castrillo A, Chini EN, Valledor AF. Matalonga J, et al. Among authors: castrillo a. Cell Rep. 2017 Jan 31;18(5):1241-1255. doi: 10.1016/j.celrep.2017.01.007. Cell Rep. 2017. PMID: 28147278 Free article.
Liver X Receptor Nuclear Receptors Are Transcriptional Regulators of Dendritic Cell Chemotaxis.
Beceiro S, Pap A, Czimmerer Z, Sallam T, Guillén JA, Gallardo G, Hong C, A-Gonzalez N, Tabraue C, Diaz M, Lopez F, Matalonga J, Valledor AF, Dominguez P, Ardavin C, Delgado-Martin C, Partida-Sanchez S, Rodriguez-Fernandez JL, Nagy L, Tontonoz P, Castrillo A. Beceiro S, et al. Among authors: castrillo a, a gonzalez n. Mol Cell Biol. 2018 Apr 30;38(10):e00534-17. doi: 10.1128/MCB.00534-17. Print 2018 May 15. Mol Cell Biol. 2018. PMID: 29507185 Free PMC article.
Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation.
Gage MC, Bécares N, Louie R, Waddington KE, Zhang Y, Tittanegro TH, Rodríguez-Lorenzo S, Jathanna A, Pourcet B, Pello OM, De la Rosa JV, Castrillo A, Pineda-Torra I. Gage MC, et al. Among authors: castrillo a. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6556-E6565. doi: 10.1073/pnas.1721245115. Epub 2018 Jun 27. Proc Natl Acad Sci U S A. 2018. PMID: 29950315 Free PMC article.
155 results