MacDonald JA - Search Results

1

Tissue-selective alternate promoters guide NLRP6 expression.

Bracey NA, Platnich JM, Lau A, Chung H, Hyndman ME, MacDonald JA, Chun J, Beck PL, Girardin SE, Gordon PM, Muruve DA. Bracey NA, et al. Among authors: macdonald ja. Life Sci Alliance. 2020 Dec 29;4(3):e202000897. doi: 10.26508/lsa.202000897. Print 2021 Mar. Life Sci Alliance. 2020. PMID: 33376129 Free PMC article.

2

Targeting hypoxia-inducible factor-1 (HIF-1) signaling in therapeutics: implications for the treatment of inflammatory bowel disease.

Hirota SA, Beck PL, MacDonald JA. Hirota SA, et al. Among authors: macdonald ja. Recent Pat Inflamm Allergy Drug Discov. 2009 Jan;3(1):1-16. doi: 10.2174/187221309787158434. Recent Pat Inflamm Allergy Drug Discov. 2009. PMID: 19149741 Review.

3

Mitogen-activated protein kinase pathways contribute to hypercontractility and increased Ca2+ sensitization in murine experimental colitis.

Ihara E, Beck PL, Chappellaz M, Wong J, Medlicott SA, MacDonald JA. Ihara E, et al. Among authors: macdonald ja. Mol Pharmacol. 2009 May;75(5):1031-41. doi: 10.1124/mol.108.049858. Epub 2009 Feb 3. Mol Pharmacol. 2009. PMID: 19190174

4

Exploring the interplay of barrier function and leukocyte recruitment in intestinal inflammation by targeting fucosyltransferase VII and trefoil factor 3.

Beck PL, Ihara E, Hirota SA, MacDonald JA, Meng D, Nanthakumar NN, Podolsky DK, Xavier RJ. Beck PL, et al. Among authors: macdonald ja. Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G43-53. doi: 10.1152/ajpgi.00228.2009. Epub 2010 Mar 18. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 20299601 Free PMC article.

5

Hypoxia-inducible factor signaling provides protection in Clostridium difficile-induced intestinal injury.

Hirota SA, Fines K, Ng J, Traboulsi D, Lee J, Ihara E, Li Y, Willmore WG, Chung D, Scully MM, Louie T, Medlicott S, Lejeune M, Chadee K, Armstrong G, Colgan SP, Muruve DA, MacDonald JA, Beck PL. Hirota SA, et al. Among authors: macdonald ja. Gastroenterology. 2010 Jul;139(1):259-69.e3. doi: 10.1053/j.gastro.2010.03.045. Epub 2010 Mar 27. Gastroenterology. 2010. PMID: 20347817 Free PMC article.

6

Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome.

Ng J, Hirota SA, Gross O, Li Y, Ulke-Lemee A, Potentier MS, Schenck LP, Vilaysane A, Seamone ME, Feng H, Armstrong GD, Tschopp J, Macdonald JA, Muruve DA, Beck PL. Ng J, et al. Among authors: macdonald ja. Gastroenterology. 2010 Aug;139(2):542-52, 552.e1-3. doi: 10.1053/j.gastro.2010.04.005. Epub 2010 Apr 13. Gastroenterology. 2010. PMID: 20398664

7

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.

Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, MacDonald JA, Beck PL. Hirota SA, et al. Among authors: macdonald ja. Inflamm Bowel Dis. 2011 Jun;17(6):1359-72. doi: 10.1002/ibd.21478. Epub 2010 Sep 24. Inflamm Bowel Dis. 2011. PMID: 20872834 Free PMC article.

8

Differential effects of salvinorin A on endotoxin-induced hypermotility and neurogenic ion transport in mouse ileum.

Fichna J, Dicay M, Hirota SA, Traboulsi D, Macdonald JA, Janecka A, Beck PL, Zjawiony JK, Macnaughton WK, Storr MA. Fichna J, et al. Among authors: macdonald ja. Neurogastroenterol Motil. 2011 Jun;23(6):583-e212. doi: 10.1111/j.1365-2982.2011.01699.x. Epub 2011 Mar 17. Neurogastroenterol Motil. 2011. PMID: 21414104

9

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter.

Hirota JA, Hirota SA, Warner SM, Stefanowicz D, Shaheen F, Beck PL, Macdonald JA, Hackett TL, Sin DD, Van Eeden S, Knight DA. Hirota JA, et al. Among authors: macdonald ja. J Allergy Clin Immunol. 2012 Apr;129(4):1116-25.e6. doi: 10.1016/j.jaci.2011.11.033. Epub 2012 Jan 9. J Allergy Clin Immunol. 2012. PMID: 22227418

10

Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis.

Gulbransen BD, Bashashati M, Hirota SA, Gui X, Roberts JA, MacDonald JA, Muruve DA, McKay DM, Beck PL, Mawe GM, Thompson RJ, Sharkey KA. Gulbransen BD, et al. Among authors: macdonald ja. Nat Med. 2012 Mar 18;18(4):600-4. doi: 10.1038/nm.2679. Nat Med. 2012. PMID: 22426419 Free PMC article.

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