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Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.
Bezdan D, Grigorev K, Meydan C, Pelissier Vatter FA, Cioffi M, Rao V, MacKay M, Nakahira K, Burnham P, Afshinnekoo E, Westover C, Butler D, Mozsary C, Donahoe T, Foox J, Mishra T, Lucotti S, Rana BK, Melnick AM, Zhang H, Matei I, Kelsen D, Yu K, Lyden DC, Taylor L, Bailey SM, Snyder MP, Garrett-Bakelman FE, Ossowski S, De Vlaminck I, Mason CE. Bezdan D, et al. Among authors: taylor l. iScience. 2020 Nov 25;23(12):101844. doi: 10.1016/j.isci.2020.101844. eCollection 2020 Dec 18. iScience. 2020. PMID: 33376973 Free PMC article.
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.
Garrett-Bakelman FE, Darshi M, Green SJ, Gur RC, Lin L, Macias BR, McKenna MJ, Meydan C, Mishra T, Nasrini J, Piening BD, Rizzardi LF, Sharma K, Siamwala JH, Taylor L, Vitaterna MH, Afkarian M, Afshinnekoo E, Ahadi S, Ambati A, Arya M, Bezdan D, Callahan CM, Chen S, Choi AMK, Chlipala GE, Contrepois K, Covington M, Crucian BE, De Vivo I, Dinges DF, Ebert DJ, Feinberg JI, Gandara JA, George KA, Goutsias J, Grills GS, Hargens AR, Heer M, Hillary RP, Hoofnagle AN, Hook VYH, Jenkinson G, Jiang P, Keshavarzian A, Laurie SS, Lee-McMullen B, Lumpkins SB, MacKay M, Maienschein-Cline MG, Melnick AM, Moore TM, Nakahira K, Patel HH, Pietrzyk R, Rao V, Saito R, Salins DN, Schilling JM, Sears DD, Sheridan CK, Stenger MB, Tryggvadottir R, Urban AE, Vaisar T, Van Espen B, Zhang J, Ziegler MG, Zwart SR, Charles JB, Kundrot CE, Scott GBI, Bailey SM, Basner M, Feinberg AP, Lee SMC, Mason CE, Mignot E, Rana BK, Smith SM, Snyder MP, Turek FW. Garrett-Bakelman FE, et al. Among authors: taylor l. Science. 2019 Apr 12;364(6436):eaau8650. doi: 10.1126/science.aau8650. Science. 2019. PMID: 30975860 Free PMC article.
Telomere Length Dynamics and DNA Damage Responses Associated with Long-Duration Spaceflight.
Luxton JJ, McKenna MJ, Lewis A, Taylor LE, George KA, Dixit SM, Moniz M, Benegas W, Mackay MJ, Mozsary C, Butler D, Bezdan D, Meydan C, Crucian BE, Zwart SR, Smith SM, Mason CE, Bailey SM. Luxton JJ, et al. Cell Rep. 2020 Dec 8;33(10):108457. doi: 10.1016/j.celrep.2020.108457. Epub 2020 Nov 25. Cell Rep. 2020. PMID: 33242406 Free article.
Temporal Telomere and DNA Damage Responses in the Space Radiation Environment.
Luxton JJ, McKenna MJ, Taylor LE, George KA, Zwart SR, Crucian BE, Drel VR, Garrett-Bakelman FE, Mackay MJ, Butler D, Foox J, Grigorev K, Bezdan D, Meydan C, Smith SM, Sharma K, Mason CE, Bailey SM. Luxton JJ, et al. Cell Rep. 2020 Dec 8;33(10):108435. doi: 10.1016/j.celrep.2020.108435. Epub 2020 Nov 25. Cell Rep. 2020. PMID: 33242411 Free article.
Haplotype diversity and sequence heterogeneity of human telomeres.
Grigorev K, Foox J, Bezdan D, Butler D, Luxton JJ, Reed J, McKenna MJ, Taylor L, George KA, Meydan C, Bailey SM, Mason CE. Grigorev K, et al. Among authors: taylor l. Genome Res. 2021 Jul;31(7):1269-1279. doi: 10.1101/gr.274639.120. Epub 2021 Jun 23. Genome Res. 2021. PMID: 34162698 Free PMC article.
Ad Astra - telomeres in space!
Bailey SM, Luxton JJ, McKenna MJ, Taylor LE, George KA, Jhavar SG, Swanson GP. Bailey SM, et al. Int J Radiat Biol. 2022;98(3):395-403. doi: 10.1080/09553002.2021.1956010. Epub 2021 Jul 26. Int J Radiat Biol. 2022. PMID: 34270368 Review.
Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight.
Garcia-Medina JS, Sienkiewicz K, Narayanan SA, Overbey EG, Grigorev K, Ryon KA, Burke M, Proszynski J, Tierney B, Schmidt CM, Mencia-Trinchant N, Klotz R, Ortiz V, Foox J, Chin C, Najjar D, Matei I, Chan I, Cruchaga C, Kleinman A, Kim J, Lucaci A, Loy C, Mzava O, De Vlaminck I, Singaraju A, Taylor LE, Schmidt JC, Schmidt MA, Blease K, Moreno J, Boddicker A, Zhao J, Lajoie B, Altomare A, Kruglyak S, Levy S, Yu M, Hassane DC, Bailey SM, Bolton K, Mateus J, Mason CE. Garcia-Medina JS, et al. Precis Clin Med. 2024 Apr 8;7(1):pbae007. doi: 10.1093/pcmedi/pbae007. eCollection 2024 Mar. Precis Clin Med. 2024. PMID: 38634106 Free PMC article.
4,516 results