Ramsden DA - Search Results

1

Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency.

Kumar RJ, Chao HX, Simpson DA, Feng W, Cho MG, Roberts VR, Sullivan AR, Shah SJ, Wozny AS, Fagan-Solis K, Kumar S, Luthman A, Ramsden DA, Purvis JE, Gupta GP. Kumar RJ, et al. Among authors: ramsden da. NAR Cancer. 2020 Dec;2(4):zcaa038. doi: 10.1093/narcan/zcaa038. Epub 2020 Dec 21. NAR Cancer. 2020. PMID: 33385162 Free PMC article.

2

Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.

Wyatt DW, Feng W, Conlin MP, Yousefzadeh MJ, Roberts SA, Mieczkowski P, Wood RD, Gupta GP, Ramsden DA. Wyatt DW, et al. Among authors: ramsden da. Mol Cell. 2016 Aug 18;63(4):662-673. doi: 10.1016/j.molcel.2016.06.020. Epub 2016 Jul 21. Mol Cell. 2016. PMID: 27453047 Free PMC article.

3

Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining.

Pryor JM, Conlin MP, Carvajal-Garcia J, Luedeman ME, Luthman AJ, Small GW, Ramsden DA. Pryor JM, et al. Among authors: ramsden da. Science. 2018 Sep 14;361(6407):1126-1129. doi: 10.1126/science.aat2477. Science. 2018. PMID: 30213916 Free PMC article.

4

Genetic determinants of cellular addiction to DNA polymerase theta.

Feng W, Simpson DA, Carvajal-Garcia J, Price BA, Kumar RJ, Mose LE, Wood RD, Rashid N, Purvis JE, Parker JS, Ramsden DA, Gupta GP. Feng W, et al. Among authors: ramsden da. Nat Commun. 2019 Sep 19;10(1):4286. doi: 10.1038/s41467-019-12234-1. Nat Commun. 2019. PMID: 31537809 Free PMC article.

5

Mechanistic basis for microhomology identification and genome scarring by polymerase theta.

Carvajal-Garcia J, Cho JE, Carvajal-Garcia P, Feng W, Wood RD, Sekelsky J, Gupta GP, Roberts SA, Ramsden DA. Carvajal-Garcia J, et al. Among authors: ramsden da. Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8476-8485. doi: 10.1073/pnas.1921791117. Epub 2020 Mar 31. Proc Natl Acad Sci U S A. 2020. PMID: 32234782 Free PMC article.

6

DNA polymerase theta suppresses mitotic crossing over.

Carvajal-Garcia J, Crown KN, Ramsden DA, Sekelsky J. Carvajal-Garcia J, et al. Among authors: ramsden da. PLoS Genet. 2021 Mar 22;17(3):e1009267. doi: 10.1371/journal.pgen.1009267. eCollection 2021 Mar. PLoS Genet. 2021. PMID: 33750946 Free PMC article.

7

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks.

Feng W, Simpson DA, Cho JE, Carvajal-Garcia J, Smith CM, Headley KM, Hathaway N, Ramsden DA, Gupta GP. Feng W, et al. Among authors: ramsden da. Nucleic Acids Res. 2021 May 21;49(9):5095-5105. doi: 10.1093/nar/gkab299. Nucleic Acids Res. 2021. PMID: 33963863 Free PMC article.

8

Mechanism, cellular functions and cancer roles of polymerase-theta-mediated DNA end joining.

Ramsden DA, Carvajal-Garcia J, Gupta GP. Ramsden DA, et al. Nat Rev Mol Cell Biol. 2022 Feb;23(2):125-140. doi: 10.1038/s41580-021-00405-2. Epub 2021 Sep 14. Nat Rev Mol Cell Biol. 2022. PMID: 34522048 Review.

9

Poly(ADP) ribose polymerase promotes DNA polymerase theta-mediated end joining by activation of end resection.

Luedeman ME, Stroik S, Feng W, Luthman AJ, Gupta GP, Ramsden DA. Luedeman ME, et al. Among authors: ramsden da. Nat Commun. 2022 Aug 4;13(1):4547. doi: 10.1038/s41467-022-32166-7. Nat Commun. 2022. PMID: 35927262 Free PMC article.

10

Templated insertions-DNA repair gets acrobatic.

Stroik S, Luthman AJ, Ramsden DA. Stroik S, et al. Among authors: ramsden da. Environ Mol Mutagen. 2024 Apr;65 Suppl 1(Suppl 1):82-89. doi: 10.1002/em.22564. Epub 2023 Jul 28. Environ Mol Mutagen. 2024. PMID: 37438951 Review.

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