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Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival.
Guilhamon P, Chesnelong C, Kushida MM, Nikolic A, Singhal D, MacLeod G, Madani Tonekaboni SA, Cavalli FM, Arlidge C, Rajakulendran N, Rastegar N, Hao X, Hassam R, Smith LJ, Whetstone H, Coutinho FJ, Nadorp B, Ellestad KI, Luchman HA, Chan JA, Shoichet MS, Taylor MD, Haibe-Kains B, Weiss S, Angers S, Gallo M, Dirks PB, Lupien M. Guilhamon P, et al. Among authors: luchman ha. Elife. 2021 Jan 11;10:e64090. doi: 10.7554/eLife.64090. Elife. 2021. PMID: 33427645 Free PMC article.
An in vivo patient-derived model of endogenous IDH1-mutant glioma.
Luchman HA, Stechishin OD, Dang NH, Blough MD, Chesnelong C, Kelly JJ, Nguyen SA, Chan JA, Weljie AM, Cairncross JG, Weiss S. Luchman HA, et al. Neuro Oncol. 2012 Feb;14(2):184-91. doi: 10.1093/neuonc/nor207. Epub 2011 Dec 13. Neuro Oncol. 2012. PMID: 22166263 Free PMC article.
DNA hypermethylation and 1p Loss silence NHE-1 in oligodendroglioma.
Blough MD, Al-Najjar M, Chesnelong C, Binding CE, Rogers AD, Luchman HA, Kelly JJ, Fliegel L, Morozova O, Yip S, Marra M, Weiss S, Chan JA, Cairncross JG. Blough MD, et al. Among authors: luchman ha. Ann Neurol. 2012 Jun;71(6):845-9. doi: 10.1002/ana.23610. Ann Neurol. 2012. PMID: 22718548
Lactate dehydrogenase A silencing in IDH mutant gliomas.
Chesnelong C, Chaumeil MM, Blough MD, Al-Najjar M, Stechishin OD, Chan JA, Pieper RO, Ronen SM, Weiss S, Luchman HA, Cairncross JG. Chesnelong C, et al. Among authors: luchman ha. Neuro Oncol. 2014 May;16(5):686-95. doi: 10.1093/neuonc/not243. Epub 2013 Dec 22. Neuro Oncol. 2014. PMID: 24366912 Free PMC article.
Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma.
Haftchenary S, Luchman HA, Jouk AO, Veloso AJ, Page BD, Cheng XR, Dawson SS, Grinshtein N, Shahani VM, Kerman K, Kaplan DR, Griffin C, Aman AM, Al-Awar R, Weiss S, Gunning PT. Haftchenary S, et al. Among authors: luchman ha. ACS Med Chem Lett. 2013 Sep 8;4(11):1102-7. doi: 10.1021/ml4003138. eCollection 2013 Nov 14. ACS Med Chem Lett. 2013. PMID: 24900612 Free PMC article.
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
Izquierdo-Garcia JL, Viswanath P, Eriksson P, Cai L, Radoul M, Chaumeil MM, Blough M, Luchman HA, Weiss S, Cairncross JG, Phillips JJ, Pieper RO, Ronen SM. Izquierdo-Garcia JL, et al. Among authors: luchman ha. Cancer Res. 2015 Aug 1;75(15):2999-3009. doi: 10.1158/0008-5472.CAN-15-0840. Epub 2015 Jun 4. Cancer Res. 2015. PMID: 26045167 Free PMC article.
42 results