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Mutation-specific effects of NRAS oncogenes in colorectal cancer cells.
Kuhn N, Klinger B, Uhlitz F, Sieber A, Rivera M, Klotz-Noack K, Fichtner I, Hoffmann J, Blüthgen N, Falk C, Sers C, Schäfer R. Kuhn N, et al. Among authors: fichtner i. Adv Biol Regul. 2021 Jan;79:100778. doi: 10.1016/j.jbior.2020.100778. Epub 2020 Dec 31. Adv Biol Regul. 2021. PMID: 33431353
Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine.
Rivera M, Fichtner I, Wulf-Goldenberg A, Sers C, Merk J, Patone G, Alp KM, Kanashova T, Mertins P, Hoffmann J, Stein U, Walther W. Rivera M, et al. Among authors: fichtner i. Neoplasia. 2021 Jan;23(1):21-35. doi: 10.1016/j.neo.2020.11.005. Epub 2020 Nov 16. Neoplasia. 2021. PMID: 33212364 Free PMC article.
A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option.
Klinghammer K, Raguse JD, Plath T, Albers AE, Joehrens K, Zakarneh A, Brzezicha B, Wulf-Goldenberg A, Keilholz U, Hoffmann J, Fichtner I. Klinghammer K, et al. Among authors: fichtner i. Int J Cancer. 2015 Jun 15;136(12):2940-8. doi: 10.1002/ijc.29344. Epub 2014 Nov 26. Int J Cancer. 2015. PMID: 25404014
228 results