Fang J - Search Results

1

AlzGPS: a genome-wide positioning systems platform to catalyze multi-omics for Alzheimer's drug discovery.

Zhou Y, Fang J, Bekris LM, Kim YH, Pieper AA, Leverenz JB, Cummings J, Cheng F. Zhou Y, et al. Among authors: fang j. Alzheimers Res Ther. 2021 Jan 13;13(1):24. doi: 10.1186/s13195-020-00760-w. Alzheimers Res Ther. 2021. PMID: 33441136 Free PMC article.

2

Systems Pharmacology-Based Discovery of Natural Products for Precision Oncology Through Targeting Cancer Mutated Genes.

Fang J, Cai C, Wang Q, Lin P, Zhao Z, Cheng F. Fang J, et al. CPT Pharmacometrics Syst Pharmacol. 2017 Mar;6(3):177-187. doi: 10.1002/psp4.12172. Epub 2017 Mar 14. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28294568 Free PMC article.

3

In silico polypharmacology of natural products.

Fang J, Liu C, Wang Q, Lin P, Cheng F. Fang J, et al. Brief Bioinform. 2018 Nov 27;19(6):1153-1171. doi: 10.1093/bib/bbx045. Brief Bioinform. 2018. PMID: 28460068 Review.

4

Quantitative and Systems Pharmacology. 1. In Silico Prediction of Drug-Target Interactions of Natural Products Enables New Targeted Cancer Therapy.

Fang J, Wu Z, Cai C, Wang Q, Tang Y, Cheng F. Fang J, et al. J Chem Inf Model. 2017 Nov 27;57(11):2657-2671. doi: 10.1021/acs.jcim.7b00216. Epub 2017 Oct 13. J Chem Inf Model. 2017. PMID: 28956927 Free PMC article.

5

Quantitative and Systems Pharmacology 3. Network-Based Identification of New Targets for Natural Products Enables Potential Uses in Aging-Associated Disorders.

Fang J, Gao L, Ma H, Wu Q, Wu T, Wu J, Wang Q, Cheng F. Fang J, et al. Front Pharmacol. 2017 Oct 18;8:747. doi: 10.3389/fphar.2017.00747. eCollection 2017. Front Pharmacol. 2017. PMID: 29093681 Free PMC article.

6

In Silico Pharmacoepidemiologic Evaluation of Drug-Induced Cardiovascular Complications Using Combined Classifiers.

Cai C, Fang J, Guo P, Wang Q, Hong H, Moslehi J, Cheng F. Cai C, et al. Among authors: fang j. J Chem Inf Model. 2018 May 29;58(5):943-956. doi: 10.1021/acs.jcim.7b00641. Epub 2018 May 10. J Chem Inf Model. 2018. PMID: 29712429 Free PMC article.

7

Quantitative and systems pharmacology 4. Network-based analysis of drug pleiotropy on coronary artery disease.

Fang J, Cai C, Chai Y, Zhou J, Huang Y, Gao L, Wang Q, Cheng F. Fang J, et al. Eur J Med Chem. 2019 Jan 1;161:192-204. doi: 10.1016/j.ejmech.2018.10.020. Epub 2018 Oct 15. Eur J Med Chem. 2019. PMID: 30359818 Free PMC article.

8

Deep Learning-Based Prediction of Drug-Induced Cardiotoxicity.

Cai C, Guo P, Zhou Y, Zhou J, Wang Q, Zhang F, Fang J, Cheng F. Cai C, et al. Among authors: fang j. J Chem Inf Model. 2019 Mar 25;59(3):1073-1084. doi: 10.1021/acs.jcim.8b00769. Epub 2019 Feb 15. J Chem Inf Model. 2019. PMID: 30715873 Free PMC article.

9

A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling.

Huang Y, Fang J, Lu W, Wang Z, Wang Q, Hou Y, Jiang X, Reizes O, Lathia J, Nussinov R, Eng C, Cheng F. Huang Y, et al. Among authors: fang j. Cell Chem Biol. 2019 Aug 15;26(8):1143-1158.e6. doi: 10.1016/j.chembiol.2019.05.004. Epub 2019 Jun 6. Cell Chem Biol. 2019. PMID: 31178408 Free PMC article.

10

A genome-wide positioning systems network algorithm for in silico drug repurposing.

Cheng F, Lu W, Liu C, Fang J, Hou Y, Handy DE, Wang R, Zhao Y, Yang Y, Huang J, Hill DE, Vidal M, Eng C, Loscalzo J. Cheng F, et al. Among authors: fang j. Nat Commun. 2019 Aug 2;10(1):3476. doi: 10.1038/s41467-019-10744-6. Nat Commun. 2019. PMID: 31375661 Free PMC article.

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