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Page 1
Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease.
Sidhom EH, Kim C, Kost-Alimova M, Ting MT, Keller K, Avila-Pacheco J, Watts AJ, Vernon KA, Marshall JL, Reyes-Bricio E, Racette M, Wieder N, Kleiner G, Grinkevich EJ, Chen F, Weins A, Clish CB, Shaw JL, Quinzii CM, Greka A. Sidhom EH, et al. Among authors: keller k. J Clin Invest. 2021 Mar 1;131(5):e141380. doi: 10.1172/JCI141380. J Clin Invest. 2021. PMID: 33444290 Free PMC article.
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic.
Alimova M, Sidhom EH, Satyam A, Dvela-Levitt M, Melanson M, Chamberlain BT, Alper SL, Santos J, Gutierrez J, Subramanian A, Grinkevich E, Bricio ER, Kim C, Clark A, Watts A, Thompson R, Marshall J, Pablo JL, Coraor J, Roignot J, Vernon KA, Keller K, Campbell A, Emani M, Racette M, Bazua-Valenti S, Padovano V, Weins A, McAdoo SP, Tam FWK, Ronco L, Wagner F, Tsokos GC, Shaw JL, Greka A. Alimova M, et al. Among authors: keller k. bioRxiv [Preprint]. 2020 Jun 30:2020.06.30.180380. doi: 10.1101/2020.06.30.180380. bioRxiv. 2020. Update in: Cell Rep Med. 2020 Oct 29;1(8):100137. doi: 10.1016/j.xcrm.2020.100137 PMID: 32637960 Free PMC article. Updated. Preprint.
A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury.
Kost-Alimova M, Sidhom EH, Satyam A, Chamberlain BT, Dvela-Levitt M, Melanson M, Alper SL, Santos J, Gutierrez J, Subramanian A, Byrne PJ, Grinkevich E, Reyes-Bricio E, Kim C, Clark AR, Watts AJB, Thompson R, Marshall J, Pablo JL, Coraor J, Roignot J, Vernon KA, Keller K, Campbell A, Emani M, Racette M, Bazua-Valenti S, Padovano V, Weins A, McAdoo SP, Tam FWK, Ronco L, Wagner F, Tsokos GC, Shaw JL, Greka A. Kost-Alimova M, et al. Among authors: keller k. Cell Rep Med. 2020 Oct 29;1(8):100137. doi: 10.1016/j.xcrm.2020.100137. eCollection 2020 Nov 17. Cell Rep Med. 2020. PMID: 33294858 Free PMC article.
Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology.
Watts AJB, Keller KH, Lerner G, Rosales I, Collins AB, Sekulic M, Waikar SS, Chandraker A, Riella LV, Alexander MP, Troost JP, Chen J, Fermin D, Yee JL, Sampson MG, Beck LH Jr, Henderson JM, Greka A, Rennke HG, Weins A. Watts AJB, et al. J Am Soc Nephrol. 2022 Jan;33(1):238-252. doi: 10.1681/ASN.2021060794. Epub 2021 Nov 3. J Am Soc Nephrol. 2022. PMID: 34732507 Free PMC article.
Authors' Reply.
Watts AJB, Keller KH, Weins A. Watts AJB, et al. J Am Soc Nephrol. 2022 Mar;33(3):654. doi: 10.1681/ASN.2021121540. Epub 2022 Jan 21. J Am Soc Nephrol. 2022. PMID: 35064049 Free PMC article. No abstract available.
High-resolution Slide-seqV2 spatial transcriptomics enables discovery of disease-specific cell neighborhoods and pathways.
Marshall JL, Noel T, Wang QS, Chen H, Murray E, Subramanian A, Vernon KA, Bazua-Valenti S, Liguori K, Keller K, Stickels RR, McBean B, Heneghan RM, Weins A, Macosko EZ, Chen F, Greka A. Marshall JL, et al. Among authors: keller k. iScience. 2022 Mar 16;25(4):104097. doi: 10.1016/j.isci.2022.104097. eCollection 2022 Apr 15. iScience. 2022. PMID: 35372810 Free PMC article.
Protective role for kidney TREM2high macrophages in obesity- and diabetes-induced kidney injury.
Subramanian A, Vernon KA, Zhou Y, Marshall JL, Alimova M, Arevalo C, Zhang F, Slyper M, Waldman J, Montesinos MS, Dionne D, Nguyen LT, Cuoco MS, Dubinsky D, Purnell J, Keller K, Sturner SH, Grinkevich E, Ghoshal A, Kotek A, Trivioli G, Richoz N, Humphrey MB, Darby IG, Miller SJ, Xu Y, Weins A, Chloe-Villani A, Chang SL, Kretzler M, Rosenblatt-Rosen O, Shaw JL, Zimmerman KA, Clatworthy MR, Regev A, Greka A. Subramanian A, et al. Among authors: keller k. Cell Rep. 2024 Jun 25;43(6):114253. doi: 10.1016/j.celrep.2024.114253. Epub 2024 May 22. Cell Rep. 2024. PMID: 38781074 Free PMC article.
Pre-transplant anti-nephrin antibodies are specific predictors of recurrent diffuse podocytopathy in the kidney allograft.
Batal I, Watts AJB, Gibier JB, Hamroun A, Top I, Provot F, Keller K, Ye X, Fernandez HE, Leal R, Andeen NK, Crew RJ, Dube GK, Vasilescu ER, Ratner LE, Bowman N, Bomback AS, Sanna-Cherchi S, Kiryluk K, Weins A. Batal I, et al. Among authors: keller k. Kidney Int. 2024 Oct;106(4):749-752. doi: 10.1016/j.kint.2024.07.022. Epub 2024 Aug 9. Kidney Int. 2024. PMID: 39127225 No abstract available.
1,333 results