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MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint.
Smith BAH, Deutzmann A, Correa KM, Delaveris CS, Dhanasekaran R, Dove CG, Sullivan DK, Wisnovsky S, Stark JC, Pluvinage JV, Swaminathan S, Riley NM, Rajan A, Majeti R, Felsher DW, Bertozzi CR. Smith BAH, et al. Among authors: swaminathan s. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2215376120. doi: 10.1073/pnas.2215376120. Epub 2023 Mar 10. Proc Natl Acad Sci U S A. 2023. PMID: 36897988 Free PMC article.
Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of IL-15-producing natural killer cells in B-cell acute lymphoblastic leukemia.
Kumar A, Taghi Khani A, Duault C, Aramburo S, Sanchez Ortiz A, Lee SJ, Chan A, McDonald T, Huang M, Lacayo NJ, Sakamoto KM, Yu J, Hurtz C, Carroll M, Tasian SK, Ghoda L, Marcucci G, Gu Z, Rosen ST, Armenian S, Izraeli S, Chen CW, Caligiuri MA, Forman SJ, Maecker HT, Swaminathan S. Kumar A, et al. Among authors: swaminathan s. J Immunother Cancer. 2023 May;11(5):e006649. doi: 10.1136/jitc-2022-006649. J Immunother Cancer. 2023. PMID: 37217248 Free PMC article.
Activated natural killer cells predict poor clinical prognosis in high-risk B- and T-cell acute lymphoblastic leukemia.
Duault C, Kumar A, Taghi Khani A, Lee SJ, Yang L, Huang M, Hurtz C, Manning B, Ghoda L, McDonald T, Lacayo NJ, Sakamoto KM, Carroll M, Tasian SK, Marcucci G, Yu J, Caligiuri MA, Maecker HT, Swaminathan S. Duault C, et al. Among authors: swaminathan s. Blood. 2021 Oct 21;138(16):1465-1480. doi: 10.1182/blood.2020009871. Blood. 2021. PMID: 34077953 Free PMC article.
Isoform-specific knockdown of long and intermediate prolactin receptors interferes with evolution of B-cell neoplasms.
Taghi Khani A, Kumar A, Sanchez Ortiz A, Radecki KC, Aramburo S, Lee SJ, Hu Z, Damirchi B, Lorenson MY, Wu X, Gu Z, Stohl W, Sanz I, Meffre E, Müschen M, Forman SJ, Koff JL, Walker AM, Swaminathan S. Taghi Khani A, et al. Among authors: swaminathan s. Commun Biol. 2023 Mar 20;6(1):295. doi: 10.1038/s42003-023-04667-8. Commun Biol. 2023. PMID: 36941341 Free PMC article.
Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia.
Gang EJ, Hsieh YT, Pham J, Zhao Y, Nguyen C, Huantes S, Park E, Naing K, Klemm L, Swaminathan S, Conway EM, Pelus LM, Crispino J, Mullighan CG, McMillan M, Müschen M, Kahn M, Kim YM. Gang EJ, et al. Among authors: swaminathan s. Oncogene. 2014 Apr 24;33(17):2169-78. doi: 10.1038/onc.2013.169. Epub 2013 Jun 3. Oncogene. 2014. PMID: 23728349 Free PMC article.
1,715 results