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Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes.
Garcia-Bates TM, Palma ML, Anderko RR, Hsu DC, Ananworanich J, Korber BT, Gaiha GD, Phanuphak N, Thomas R, Tovanabutra S, Walker BD, Mellors JW, Piazza PA, Kroon E, Riddler SA, Michael NL, Rinaldo CR, Mailliard RB; I4C and RV254 Study Groups. Garcia-Bates TM, et al. Among authors: gaiha gd. EBioMedicine. 2021 Jan;63:103175. doi: 10.1016/j.ebiom.2020.103175. Epub 2021 Jan 12. EBioMedicine. 2021. PMID: 33450518 Free PMC article.
Reactivation of latent HIV-1 by inhibition of BRD4.
Zhu J, Gaiha GD, John SP, Pertel T, Chin CR, Gao G, Qu H, Walker BD, Elledge SJ, Brass AL. Zhu J, et al. Among authors: gaiha gd. Cell Rep. 2012 Oct 25;2(4):807-16. doi: 10.1016/j.celrep.2012.09.008. Epub 2012 Oct 4. Cell Rep. 2012. PMID: 23041316 Free PMC article.
Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis.
Gaiha GD, McKim KJ, Woods M, Pertel T, Rohrbach J, Barteneva N, Chin CR, Liu D, Soghoian DZ, Cesa K, Wilton S, Waring MT, Chicoine A, Doering T, Wherry EJ, Kaufmann DE, Lichterfeld M, Brass AL, Walker BD. Gaiha GD, et al. Immunity. 2014 Dec 18;41(6):1001-12. doi: 10.1016/j.immuni.2014.12.011. Epub 2014 Dec 8. Immunity. 2014. PMID: 25526311 Free PMC article.
CD8(+) T Cells and cART: A Dynamic Duo?
Gaiha GD, Walker BD. Gaiha GD, et al. Immunity. 2016 Sep 20;45(3):466-468. doi: 10.1016/j.immuni.2016.09.003. Immunity. 2016. PMID: 27653598 Free article. Review.
Structural topology defines protective CD8+ T cell epitopes in the HIV proteome.
Gaiha GD, Rossin EJ, Urbach J, Landeros C, Collins DR, Nwonu C, Muzhingi I, Anahtar MN, Waring OM, Piechocka-Trocha A, Waring M, Worrall DP, Ghebremichael MS, Newman RM, Power KA, Allen TM, Chodosh J, Walker BD. Gaiha GD, et al. Science. 2019 May 3;364(6439):480-484. doi: 10.1126/science.aav5095. Science. 2019. PMID: 31048489 Free PMC article.
CD8+ T cells in HIV control, cure and prevention.
Collins DR, Gaiha GD, Walker BD. Collins DR, et al. Among authors: gaiha gd. Nat Rev Immunol. 2020 Aug;20(8):471-482. doi: 10.1038/s41577-020-0274-9. Epub 2020 Feb 12. Nat Rev Immunol. 2020. PMID: 32051540 Free PMC article. Review.
HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV.
Kaseke C, Park RJ, Singh NK, Koundakjian D, Bashirova A, Garcia Beltran WF, Takou Mbah OC, Ma J, Senjobe F, Urbach JM, Nathan A, Rossin EJ, Tano-Menka R, Khatri A, Piechocka-Trocha A, Waring MT, Birnbaum ME, Baker BM, Carrington M, Walker BD, Gaiha GD. Kaseke C, et al. Among authors: gaiha gd. Cell Rep. 2021 Jul 13;36(2):109378. doi: 10.1016/j.celrep.2021.109378. Cell Rep. 2021. PMID: 34260940 Free PMC article.
Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses.
Nathan A, Rossin EJ, Kaseke C, Park RJ, Khatri A, Koundakjian D, Urbach JM, Singh NK, Bashirova A, Tano-Menka R, Senjobe F, Waring MT, Piechocka-Trocha A, Garcia-Beltran WF, Iafrate AJ, Naranbhai V, Carrington M, Walker BD, Gaiha GD. Nathan A, et al. Among authors: gaiha gd. Cell. 2021 Aug 19;184(17):4401-4413.e10. doi: 10.1016/j.cell.2021.06.029. Epub 2021 Jun 30. Cell. 2021. PMID: 34265281 Free PMC article.
Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia.
Collins DR, Urbach JM, Racenet ZJ, Arshad U, Power KA, Newman RM, Mylvaganam GH, Ly NL, Lian X, Rull A, Rassadkina Y, Yanez AG, Peluso MJ, Deeks SG, Vidal F, Lichterfeld M, Yu XG, Gaiha GD, Allen TM, Walker BD. Collins DR, et al. Among authors: gaiha gd. Immunity. 2021 Oct 12;54(10):2372-2384.e7. doi: 10.1016/j.immuni.2021.08.007. Epub 2021 Sep 7. Immunity. 2021. PMID: 34496223 Free PMC article.
41 results