LeCluyse EL - Search Results

1

Hepatocyte size fractionation allows dissection of human liver zonation.

Ölander M, Wegler C, Flörkemeier I, Treyer A, Handin N, Pedersen JM, Vildhede A, Mateus A, LeCluyse EL, Urdzik J, Artursson P. Ölander M, et al. Among authors: lecluyse el. J Cell Physiol. 2021 Aug;236(8):5885-5894. doi: 10.1002/jcp.30273. Epub 2021 Jan 16. J Cell Physiol. 2021. PMID: 33452735

2

Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

Pedersen JM, Matsson P, Bergström CA, Hoogstraate J, Norén A, LeCluyse EL, Artursson P. Pedersen JM, et al. Among authors: lecluyse el. Toxicol Sci. 2013 Dec;136(2):328-43. doi: 10.1093/toxsci/kft197. Epub 2013 Sep 6. Toxicol Sci. 2013. PMID: 24014644 Free PMC article.

3

Development of 3D dynamic flow model of human liver and its application to prediction of metabolic clearance of 7-ethoxycoumarin.

Choi K, Pfund WP, Andersen ME, Thomas RS, Clewell HJ, LeCluyse EL. Choi K, et al. Among authors: lecluyse el. Tissue Eng Part C Methods. 2014 Aug;20(8):641-51. doi: 10.1089/ten.TEC.2013.0562. Epub 2014 Mar 4. Tissue Eng Part C Methods. 2014. PMID: 24294911

4

The evolving microenvironment of the human hepatocyte: Healthy vs. cirrhotic liver vs. isolated cells.

Kirchner VA, Tak E, Kim K, LeCluyse EL, Niedernhofer LJ, Soldatow V, Lee J, Kim J, Tolar J, Song GW, Pruett TL. Kirchner VA, et al. Among authors: lecluyse el. Tissue Cell. 2020 Feb;62:101310. doi: 10.1016/j.tice.2019.101310. Epub 2019 Oct 21. Tissue Cell. 2020. PMID: 32433018

5

Hepatocyte-Derived Exosomes Promote Liver Immune Tolerance: Possible Implications for Idiosyncratic Drug-Induced Liver Injury.

Holman NS, Church RJ, Nautiyal M, Rose KA, Thacker SE, Otieno MA, Wolf KK, LeCluyse E, Watkins PB, Mosedale M. Holman NS, et al. Toxicol Sci. 2019 Aug 1;170(2):499-508. doi: 10.1093/toxsci/kfz112. Toxicol Sci. 2019. PMID: 31093666 Free PMC article.

6

A micropatterned hepatocyte coculture model for assessment of liver toxicity using high-content imaging analysis.

Trask OJ Jr, Moore A, LeCluyse EL. Trask OJ Jr, et al. Among authors: lecluyse el. Assay Drug Dev Technol. 2014 Jan-Feb;12(1):16-27. doi: 10.1089/adt.2013.525. Epub 2014 Jan 20. Assay Drug Dev Technol. 2014. PMID: 24444127

7

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation.

LeCluyse EL. LeCluyse EL. Eur J Pharm Sci. 2001 Jul;13(4):343-68. doi: 10.1016/s0928-0987(01)00135-x. Eur J Pharm Sci. 2001. PMID: 11408150 Review.

8

Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals.

Rotroff DM, Beam AL, Dix DJ, Farmer A, Freeman KM, Houck KA, Judson RS, LeCluyse EL, Martin MT, Reif DM, Ferguson SS. Rotroff DM, et al. Among authors: lecluyse el. J Toxicol Environ Health B Crit Rev. 2010 Feb;13(2-4):329-46. doi: 10.1080/10937404.2010.483949. J Toxicol Environ Health B Crit Rev. 2010. PMID: 20574906

9

Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro.

Dash A, Simmers MB, Deering TG, Berry DJ, Feaver RE, Hastings NE, Pruett TL, LeCluyse EL, Blackman BR, Wamhoff BR. Dash A, et al. Among authors: lecluyse el. Am J Physiol Cell Physiol. 2013 Jun 1;304(11):C1053-63. doi: 10.1152/ajpcell.00331.2012. Epub 2013 Mar 13. Am J Physiol Cell Physiol. 2013. PMID: 23485712 Free PMC article.

10

Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes.

Sunman JA, Hawke RL, LeCluyse EL, Kashuba AD. Sunman JA, et al. Among authors: lecluyse el. Drug Metab Dispos. 2004 Mar;32(3):359-63. doi: 10.1124/dmd.32.3.359. Drug Metab Dispos. 2004. PMID: 14977871

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