van Beusechem VW - Search Results

1

Oncolytic Adenovirus ORCA-010 Activates Proinflammatory Myeloid Cells and Facilitates T Cell Recruitment and Activation by PD-1 Blockade in Melanoma.

Milenova I, Lopez Gonzalez M, Quixabeira DCA, Santos JM, Cervera-Carrascon V, Dong W, Hemminki A, van Beusechem VW, van de Ven R, de Gruijl TD. Milenova I, et al. Among authors: van beusechem vw. Hum Gene Ther. 2021 Feb;32(3-4):178-191. doi: 10.1089/hum.2020.277. Hum Gene Ther. 2021. PMID: 33470166

2

Selective gene transfer into primary human gastric tumors using epithelial cell adhesion molecule-targeted adenoviral vectors with ablated native tropism.

Heideman DA, van Beusechem VW, Offerhaus GJ, Wickham TJ, Roelvink PW, Craanen ME, Pinedo HM, Meijer CJ, Gerritsen WR. Heideman DA, et al. Among authors: van beusechem vw. Hum Gene Ther. 2002 Sep 20;13(14):1677-85. doi: 10.1089/104303402760293529. Hum Gene Ther. 2002. PMID: 12396621

3

Conditionally replicative adenovirus expressing a targeting adapter molecule exhibits enhanced oncolytic potency on CAR-deficient tumors.

van Beusechem VW, Mastenbroek DC, van den Doel PB, Lamfers ML, Grill J, Würdinger T, Haisma HJ, Pinedo HM, Gerritsen WR. van Beusechem VW, et al. Among authors: van den doel pb. Gene Ther. 2003 Nov;10(23):1982-91. doi: 10.1038/sj.gt.3302103. Gene Ther. 2003. PMID: 14528322

4

Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdDelta24.

Oosterhoff D, Pinedo HM, Witlox MA, Carette JE, Gerritsen WR, van Beusechem VW. Oosterhoff D, et al. Among authors: van beusechem vw. Gene Ther. 2005 Jun;12(12):1011-8. doi: 10.1038/sj.gt.3302492. Gene Ther. 2005. PMID: 15729367

5

Comparison of oncolytic adenoviruses for selective eradication of oral cancer and pre-cancerous lesions.

van Zeeburg HJ, Huizenga A, Brink A, van den Doel PB, Zhu ZB, McCormick F, Brakenhoff RH, van Beusechem VW. van Zeeburg HJ, et al. Among authors: van den doel pb, van beusechem vw. Gene Ther. 2010 Dec;17(12):1517-24. doi: 10.1038/gt.2010.99. Epub 2010 Aug 5. Gene Ther. 2010. PMID: 20686507

6

Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine.

Hangalapura BN, Oosterhoff D, Gupta T, de Groot J, Wijnands PG, van Beusechem VW, den Haan J, Tüting T, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Hangalapura BN, et al. Among authors: van den eertwegh aj, van beusechem vw. Vaccine. 2011 Mar 9;29(12):2313-21. doi: 10.1016/j.vaccine.2011.01.022. Epub 2011 Jan 25. Vaccine. 2011. PMID: 21272606 Free PMC article.

7

Potent antitumor immunity generated by a CD40-targeted adenoviral vaccine.

Hangalapura BN, Oosterhoff D, de Groot J, Boon L, Tüting T, van den Eertwegh AJ, Gerritsen WR, van Beusechem VW, Pereboev A, Curiel DT, Scheper RJ, de Gruijl TD. Hangalapura BN, et al. Among authors: van den eertwegh aj, van beusechem vw. Cancer Res. 2011 Sep 1;71(17):5827-37. doi: 10.1158/0008-5472.CAN-11-0804. Epub 2011 Jul 11. Cancer Res. 2011. PMID: 21747119 Free article.

8

ORCA-010, a novel potency-enhanced oncolytic adenovirus, exerts strong antitumor activity in preclinical models.

Dong W, van Ginkel JW, Au KY, Alemany R, Meulenberg JJ, van Beusechem VW. Dong W, et al. Among authors: van ginkel jw, van beusechem vw. Hum Gene Ther. 2014 Oct;25(10):897-904. doi: 10.1089/hum.2013.229. Epub 2014 Sep 17. Hum Gene Ther. 2014. PMID: 25093639 Free PMC article.

9

Arming oncolytic viruses to leverage antitumor immunity.

de Gruijl TD, Janssen AB, van Beusechem VW. de Gruijl TD, et al. Among authors: van beusechem vw. Expert Opin Biol Ther. 2015 Jul;15(7):959-71. doi: 10.1517/14712598.2015.1044433. Epub 2015 May 10. Expert Opin Biol Ther. 2015. PMID: 25959450 Review.

10

Functional Screening Identifies Human miRNAs that Modulate Adenovirus Propagation in Prostate Cancer Cells.

Hodzic J, Sie D, Vermeulen A, van Beusechem VW. Hodzic J, et al. Among authors: van beusechem vw. Hum Gene Ther. 2017 Sep;28(9):766-780. doi: 10.1089/hum.2016.143. Epub 2017 Jan 23. Hum Gene Ther. 2017. PMID: 28114818

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