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Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome.
Vavassori V, Mercuri E, Marcovecchio GE, Castiello MC, Schiroli G, Albano L, Margulies C, Buquicchio F, Fontana E, Beretta S, Merelli I, Cappelleri A, Rancoita PM, Lougaris V, Plebani A, Kanariou M, Lankester A, Ferrua F, Scanziani E, Cotta-Ramusino C, Villa A, Naldini L, Genovese P. Vavassori V, et al. Among authors: margulies c. EMBO Mol Med. 2021 Mar 5;13(3):e13545. doi: 10.15252/emmm.202013545. Epub 2021 Jan 21. EMBO Mol Med. 2021. PMID: 33475257 Free PMC article.
A highly efficient transgene knock-in technology in clinically relevant cell types.
Allen AG, Khan SQ, Margulies CM, Viswanathan R, Lele S, Blaha L, Scott SN, Izzo KM, Gerew A, Pattali R, Cochran NR, Holland CS, Zhao AH, Sherman SE, Jaskolka MC, Wu M, Wilson AC, Sun X, Ciulla DM, Zhang D, Nelson JD, Zhang P, Mazzucato P, Huang Y, Giannoukos G, Marco E, Nehil M, Follit JA, Chang KH, Shearman MS, Wilson CJ, Zuris JA. Allen AG, et al. Among authors: margulies cm. Nat Biotechnol. 2024 Mar;42(3):458-469. doi: 10.1038/s41587-023-01779-8. Epub 2023 May 1. Nat Biotechnol. 2024. PMID: 37127662
Pioneers conquer core histones at the chromatin frontier.
Murawska M, Ladurner AG, Margulies CE. Murawska M, et al. Among authors: margulies ce. Nat Struct Mol Biol. 2023 Aug;30(8):1050-1053. doi: 10.1038/s41594-023-01058-9. Nat Struct Mol Biol. 2023. PMID: 37563442 No abstract available.
PARP-1 Flips the Epigenetic Switch on Obesity.
Margulies CE, Ladurner AG. Margulies CE, et al. Mol Cell. 2020 Sep 17;79(6):874-875. doi: 10.1016/j.molcel.2020.08.019. Mol Cell. 2020. PMID: 32946760 Free article.
26 results