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Multi-organ proteomic landscape of COVID-19 autopsies.
Nie X, Qian L, Sun R, Huang B, Dong X, Xiao Q, Zhang Q, Lu T, Yue L, Chen S, Li X, Sun Y, Li L, Xu L, Li Y, Yang M, Xue Z, Liang S, Ding X, Yuan C, Peng L, Liu W, Yi X, Lyu M, Xiao G, Xu X, Ge W, He J, Fan J, Wu J, Luo M, Chang X, Pan H, Cai X, Zhou J, Yu J, Gao H, Xie M, Wang S, Ruan G, Chen H, Su H, Mei H, Luo D, Zhao D, Xu F, Li Y, Zhu Y, Xia J, Hu Y, Guo T. Nie X, et al. Among authors: chen s, chen h. Cell. 2021 Feb 4;184(3):775-791.e14. doi: 10.1016/j.cell.2021.01.004. Epub 2021 Jan 9. Cell. 2021. PMID: 33503446 Free PMC article. Clinical Trial.
Proteomic and Metabolomic Characterization of COVID-19 Patient Sera.
Shen B, Yi X, Sun Y, Bi X, Du J, Zhang C, Quan S, Zhang F, Sun R, Qian L, Ge W, Liu W, Liang S, Chen H, Zhang Y, Li J, Xu J, He Z, Chen B, Wang J, Yan H, Zheng Y, Wang D, Zhu J, Kong Z, Kang Z, Liang X, Ding X, Ruan G, Xiang N, Cai X, Gao H, Li L, Li S, Xiao Q, Lu T, Zhu Y, Liu H, Chen H, Guo T. Shen B, et al. Among authors: chen b, chen h. Cell. 2020 Jul 9;182(1):59-72.e15. doi: 10.1016/j.cell.2020.05.032. Epub 2020 May 28. Cell. 2020. PMID: 32492406 Free PMC article.
Convergent network effects along the axis of gene expression during prostate cancer progression.
Charmpi K, Guo T, Zhong Q, Wagner U, Sun R, Toussaint NC, Fritz CE, Yuan C, Chen H, Rupp NJ, Christiansen A, Rutishauser D, Rüschoff JH, Fankhauser C, Saba K, Poyet C, Hermanns T, Oehl K, Moore AL, Beisel C, Calzone L, Martignetti L, Zhang Q, Zhu Y, Martínez MR, Manica M, Haffner MC, Aebersold R, Wild PJ, Beyer A. Charmpi K, et al. Among authors: chen h. Genome Biol. 2020 Dec 14;21(1):302. doi: 10.1186/s13059-020-02188-9. Genome Biol. 2020. PMID: 33317623 Free PMC article.
Eleven routine clinical features predict COVID-19 severity uncovered by machine learning of longitudinal measurements.
Zhou K, Sun Y, Li L, Zang Z, Wang J, Li J, Liang J, Zhang F, Zhang Q, Ge W, Chen H, Sun X, Yue L, Wu X, Shen B, Xu J, Zhu H, Chen S, Yang H, Huang S, Peng M, Lv D, Zhang C, Zhao H, Hong L, Zhou Z, Chen H, Dong X, Tu C, Li M, Zhu Y, Chen B, Li SZ, Guo T. Zhou K, et al. Among authors: chen b, chen s, chen h. Comput Struct Biotechnol J. 2021;19:3640-3649. doi: 10.1016/j.csbj.2021.06.022. Epub 2021 Jun 17. Comput Struct Biotechnol J. 2021. PMID: 34188785 Free PMC article.
Gut microbiota, inflammation, and molecular signatures of host response to infection.
Gou W, Fu Y, Yue L, Chen GD, Cai X, Shuai M, Xu F, Yi X, Chen H, Zhu Y, Xiao ML, Jiang Z, Miao Z, Xiao C, Shen B, Wu X, Zhao H, Ling W, Wang J, Chen YM, Guo T, Zheng JS. Gou W, et al. Among authors: chen ym, chen gd, chen h. J Genet Genomics. 2021 Sep 20;48(9):792-802. doi: 10.1016/j.jgg.2021.04.002. Epub 2021 May 3. J Genet Genomics. 2021. PMID: 34257044
Circulating Proteome and Progression of Type 2 Diabetes.
Gou W, Yue L, Tang XY, Wu YY, Cai X, Shuai M, Miao Z, Fu Y, Chen H, Jiang Z, Wang J, Tian Y, Xiao C, Xiang N, Wu Z, Chen YM, Guo T, Zheng JS. Gou W, et al. Among authors: chen ym, chen h. J Clin Endocrinol Metab. 2022 May 17;107(6):1616-1625. doi: 10.1210/clinem/dgac098. J Clin Endocrinol Metab. 2022. PMID: 35184183
Stratification of follicular thyroid tumours using data-independent acquisition proteomics and a comprehensive thyroid tissue spectral library.
Sun Y, Li L, Zhou Y, Ge W, Wang H, Wu R, Liu W, Chen H, Xiao Q, Cai X, Dong Z, Zhang F, Xiao J, Wang G, He Y, Gao J, Kon OL, Iyer NG, Guan H, Teng X, Zhu Y, Zhao Y, Guo T. Sun Y, et al. Among authors: chen h. Mol Oncol. 2022 Apr;16(8):1611-1624. doi: 10.1002/1878-0261.13198. Epub 2022 Mar 12. Mol Oncol. 2022. PMID: 35194950 Free PMC article.
Enhanced inflammation and suppressed adaptive immunity in COVID-19 with prolonged RNA shedding.
Tang X, Sun R, Ge W, Mao T, Qian L, Huang C, Kang Z, Xiao Q, Luo M, Zhang Q, Li S, Chen H, Liu W, Wang B, Li S, Lin X, Xu X, Li H, Wu L, Dai J, Gao H, Li L, Lu T, Liang X, Cai X, Ruan G, Xu F, Li Y, Zhu Y, Kong Z, Huang J, Guo T. Tang X, et al. Among authors: chen h. Cell Discov. 2022 Jul 25;8(1):70. doi: 10.1038/s41421-022-00441-y. Cell Discov. 2022. PMID: 35879274 Free PMC article.
Artificial intelligence defines protein-based classification of thyroid nodules.
Sun Y, Selvarajan S, Zang Z, Liu W, Zhu Y, Zhang H, Chen W, Chen H, Li L, Cai X, Gao H, Wu Z, Zhao Y, Chen L, Teng X, Mantoo S, Lim TK, Hariraman B, Yeow S, Alkaff SMF, Lee SS, Ruan G, Zhang Q, Zhu T, Hu Y, Dong Z, Ge W, Xiao Q, Wang W, Wang G, Xiao J, He Y, Wang Z, Sun W, Qin Y, Zhu J, Zheng X, Wang L, Zheng X, Xu K, Shao Y, Zheng S, Liu K, Aebersold R, Guan H, Wu X, Luo D, Tian W, Li SZ, Kon OL, Iyer NG, Guo T. Sun Y, et al. Among authors: chen l, chen w, chen h. Cell Discov. 2022 Sep 6;8(1):85. doi: 10.1038/s41421-022-00442-x. Cell Discov. 2022. PMID: 36068205 Free PMC article.
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