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SIMON: Open-Source Knowledge Discovery Platform.
Tomic A, Tomic I, Waldron L, Geistlinger L, Kuhn M, Spreng RL, Dahora LC, Seaton KE, Tomaras G, Hill J, Duggal NA, Pollock RD, Lazarus NR, Harridge SDR, Lord JM, Khatri P, Pollard AJ, Davis MM. Tomic A, et al. Among authors: spreng rl. Patterns (N Y). 2021 Jan 8;2(1):100178. doi: 10.1016/j.patter.2020.100178. eCollection 2021 Jan 8. Patterns (N Y). 2021. PMID: 33511368 Free PMC article.
IgA and IgG1 Specific to Vi Polysaccharide of Salmonella Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model.
Dahora LC, Jin C, Spreng RL, Feely F, Mathura R, Seaton KE, Zhang L, Hill J, Jones E, Alam SM, Dennison SM, Pollard AJ, Tomaras GD. Dahora LC, et al. Among authors: spreng rl. Front Immunol. 2019 Nov 1;10:2582. doi: 10.3389/fimmu.2019.02582. eCollection 2019. Front Immunol. 2019. PMID: 31781100 Free PMC article. Clinical Trial.
Vi-specific serological correlates of protection for typhoid fever.
Jin C, Hill J, Gunn BM, Yu WH, Dahora LC, Jones E, Johnson M, Gibani MM, Spreng RL, Alam SM, Nebykova A, Juel HB, Dennison SM, Seaton KE, Fallon JK, Tomaras GD, Alter G, Pollard AJ. Jin C, et al. Among authors: spreng rl. J Exp Med. 2021 Feb 1;218(2):e20201116. doi: 10.1084/jem.20201116. J Exp Med. 2021. PMID: 33180929 Free PMC article. Clinical Trial.
Comprehensive Data Integration Approach to Assess Immune Responses and Correlates of RTS,S/AS01-Mediated Protection From Malaria Infection in Controlled Human Malaria Infection Trials.
Young WC, Carpp LN, Chaudhury S, Regules JA, Bergmann-Leitner ES, Ockenhouse C, Wille-Reece U, deCamp AC, Hughes E, Mahoney C, Pallikkuth S, Pahwa S, Dennison SM, Mudrak SV, Alam SM, Seaton KE, Spreng RL, Fallon J, Michell A, Ulloa-Montoya F, Coccia M, Jongert E, Alter G, Tomaras GD, Gottardo R. Young WC, et al. Among authors: spreng rl. Front Big Data. 2021 Jun 15;4:672460. doi: 10.3389/fdata.2021.672460. eCollection 2021. Front Big Data. 2021. PMID: 34212134 Free PMC article.
Subclass and avidity of circumsporozoite protein specific antibodies associate with protection status against malaria infection.
Seaton KE, Spreng RL, Abraha M, Reichartz M, Rojas M, Feely F 2nd, Huntwork RHC, Dutta S, Mudrak SV, Alam SM, Gregory S, Jongert E, Coccia M, Ulloa-Montoya F, Wille-Reece U, Tomaras GD, Dennison SM. Seaton KE, et al. Among authors: spreng rl. NPJ Vaccines. 2021 Aug 30;6(1):110. doi: 10.1038/s41541-021-00372-x. NPJ Vaccines. 2021. PMID: 34462438 Free PMC article.
A tool for evaluating heterogeneity in avidity of polyclonal antibodies.
Li K, Dodds M, Spreng RL, Abraha M, Huntwork RHC, Dahora LC, Nyanhete T, Dutta S, Wille-Reece U, Jongert E, Ewer KJ, Hill AVS, Jin C, Hill J, Pollard AJ, Munir Alam S, Tomaras GD, Dennison SM. Li K, et al. Among authors: spreng rl. Front Immunol. 2023 Feb 16;14:1049673. doi: 10.3389/fimmu.2023.1049673. eCollection 2023. Front Immunol. 2023. PMID: 36875126 Free PMC article.
Viral vector delivered immunogen focuses HIV-1 antibody specificity and increases durability of the circulating antibody recall response.
Williams LD, Shen X, Sawant SS, Akapirat S, Dahora LC, Tay MZ, Stanfield-Oakley S, Wills S, Goodman D, Tenney D, Spreng RL, Zhang L, Yates NL, Montefiori DC, Eller MA, Easterhoff D, Hope TJ, Rerks-Ngarm S, Pittisuttithum P, Nitayaphan S, Excler JL, Kim JH, Michael NL, Robb ML, O'Connell RJ, Karasavvas N, Vasan S, Ferrari G, Tomaras GD; RV305 study team. Williams LD, et al. Among authors: spreng rl. PLoS Pathog. 2023 May 31;19(5):e1011359. doi: 10.1371/journal.ppat.1011359. eCollection 2023 May. PLoS Pathog. 2023. PMID: 37256916 Free PMC article.
A comparative immunological assessment of multiple clinical-stage adjuvants for the R21 malaria vaccine in nonhuman primates.
Arunachalam PS, Ha N, Dennison SM, Spreng RL, Seaton KE, Xiao P, Feng Y, Zarnitsyna VI, Kazmin D, Hu M, Santagata JM, Xie X, Rogers K, Shirreff LM, Chottin C, Spencer AJ, Dutta S, Prieto K, Julien JP, Tomai M, Fox CB, Villinger F, Hill AVS, Tomaras GD, Pulendran B. Arunachalam PS, et al. Among authors: spreng rl. Sci Transl Med. 2024 Jul 31;16(758):eadn6605. doi: 10.1126/scitranslmed.adn6605. Epub 2024 Jul 31. Sci Transl Med. 2024. PMID: 39083589
Identification of RTS,S/AS01 vaccine-induced humoral biomarkers predictive of protection against controlled human malaria infection.
Spreng RL, Seaton KE, Lin L, Hilliard S, Horn GQ, Abraha M, Deal AW, Li K, Carnacchi AJ, Feeney E, Shabbir S, Zhang L, Bekker V, Mudrak SV, Dutta S, Mercer LD, Gregory S, King CR, Wille-Reece U, Jongert E, Kisalu NK, Tomaras GD, Dennison SM. Spreng RL, et al. JCI Insight. 2024 Oct 8;9(19):e178801. doi: 10.1172/jci.insight.178801. JCI Insight. 2024. PMID: 39377226 Free PMC article. Clinical Trial.
GeM-LR: Discovering predictive biomarkers for small datasets in vaccine studies.
Lin L, Spreng RL, Seaton KE, Dennison SM, Dahora LC, Schuster DJ, Sawant S, Gilbert PB, Fong Y, Kisalu N, Pollard AJ, Tomaras GD, Li J. Lin L, et al. Among authors: spreng rl. PLoS Comput Biol. 2024 Nov 14;20(11):e1012581. doi: 10.1371/journal.pcbi.1012581. eCollection 2024 Nov. PLoS Comput Biol. 2024. PMID: 39541411 Free PMC article.
20 results