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Targeting Lysyl Oxidase Family Meditated Matrix Cross-Linking as an Anti-Stromal Therapy in Solid Tumours.
Cancers (Basel). 2021 Jan 27;13(3):491. doi: 10.3390/cancers13030491.
Cancers (Basel). 2021.
PMID: 33513979
Free PMC article.
Review.
The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development.
Chitty JL, Skhinas JN, Filipe EC, Wang S, Cupello CR, Grant RD, Yam M, Papanicolaou M, Major G, Zaratzian A, Da Silva AM, Tayao M, Vennin C, Timpson P, Madsen CD, Cox TR.
Chitty JL, et al. Among authors: grant rd.
Cancer Rep (Hoboken). 2020 Feb;3(1):e1209. doi: 10.1002/cnr2.1209. Epub 2019 Aug 1.
Cancer Rep (Hoboken). 2020.
PMID: 32671954
Free PMC article.
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A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
Chitty JL, Yam M, Perryman L, Parker AL, Skhinas JN, Setargew YFI, Mok ETY, Tran E, Grant RD, Latham SL, Pereira BA, Ritchie SC, Murphy KJ, Trpceski M, Findlay AD, Melenec P, Filipe EC, Nadalini A, Velayuthar S, Major G, Wyllie K, Papanicolaou M, Ratnaseelan S, Phillips PA, Sharbeen G, Youkhana J, Russo A, Blackwell A, Hastings JF, Lucas MC, Chambers CR, Reed DA, Stoehr J, Vennin C, Pidsley R, Zaratzian A, Da Silva AM, Tayao M, Charlton B, Herrmann D, Nobis M, Clark SJ, Biankin AV, Johns AL, Croucher DR, Nagrial A, Gill AJ, Grimmond SM; Australian Pancreatic Cancer Genome Initiative (APGI); Australian Pancreatic Cancer Matrix Atlas (APMA); Pajic M, Timpson P, Jarolimek W, Cox TR.
Chitty JL, et al. Among authors: grant rd.
Nat Cancer. 2023 Sep;4(9):1326-1344. doi: 10.1038/s43018-023-00614-y. Epub 2023 Aug 28.
Nat Cancer. 2023.
PMID: 37640930
Free PMC article.
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Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood.
Perdijk O, Butler A, Macowan M, Chatzis R, Bulanda E, Grant RD, Harris NL, Wypych TP, Marsland BJ.
Perdijk O, et al. Among authors: grant rd.
Immunity. 2024 Aug 13;57(8):1939-1954.e7. doi: 10.1016/j.immuni.2024.06.010. Epub 2024 Jul 15.
Immunity. 2024.
PMID: 39013465
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