Nussinov R - Search Results

1

My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype.

Zhou Y, Zhao J, Fang J, Martin W, Li L, Nussinov R, Chan TA, Eng C, Cheng F. Zhou Y, et al. Among authors: nussinov r. Genome Biol. 2021 Jan 29;22(1):53. doi: 10.1186/s13059-021-02269-3. Genome Biol. 2021. PMID: 33514395 Free PMC article.

2

KRAS Activating Signaling Triggers Arteriovenous Malformations.

Cheng F, Nussinov R. Cheng F, et al. Among authors: nussinov r. Trends Biochem Sci. 2018 Jul;43(7):481-483. doi: 10.1016/j.tibs.2018.04.007. Epub 2018 May 7. Trends Biochem Sci. 2018. PMID: 29748115 Free PMC article.

3

Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells.

Wu D, Wang W, Chen W, Lian F, Lang L, Huang Y, Xu Y, Zhang N, Chen Y, Liu M, Nussinov R, Cheng F, Lu W, Huang J. Wu D, et al. Among authors: nussinov r. Haematologica. 2018 Sep;103(9):1472-1483. doi: 10.3324/haematol.2018.188185. Epub 2018 Jun 7. Haematologica. 2018. PMID: 29880605 Free PMC article.

4

Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health.

Cheng F, Liang H, Butte AJ, Eng C, Nussinov R. Cheng F, et al. Among authors: nussinov r. Pharmacol Rev. 2019 Jan;71(1):1-19. doi: 10.1124/pr.118.016253. Epub 2018 Dec 13. Pharmacol Rev. 2019. PMID: 30545954 Free PMC article. Review.

5

Precision medicine review: rare driver mutations and their biophysical classification.

Nussinov R, Jang H, Tsai CJ, Cheng F. Nussinov R, et al. Biophys Rev. 2019 Feb;11(1):5-19. doi: 10.1007/s12551-018-0496-2. Epub 2019 Jan 4. Biophys Rev. 2019. PMID: 30610579 Free PMC article. Review.

6

A component overlapping attribute clustering (COAC) algorithm for single-cell RNA sequencing data analysis and potential pathobiological implications.

Peng H, Zeng X, Zhou Y, Zhang D, Nussinov R, Cheng F. Peng H, et al. Among authors: nussinov r. PLoS Comput Biol. 2019 Feb 19;15(2):e1006772. doi: 10.1371/journal.pcbi.1006772. eCollection 2019 Feb. PLoS Comput Biol. 2019. PMID: 30779739 Free PMC article.

7

Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers.

Nussinov R, Jang H, Tsai CJ, Cheng F. Nussinov R, et al. PLoS Comput Biol. 2019 Mar 28;15(3):e1006658. doi: 10.1371/journal.pcbi.1006658. eCollection 2019 Mar. PLoS Comput Biol. 2019. PMID: 30921324 Free PMC article. Review.

8

deepDR: a network-based deep learning approach to in silico drug repositioning.

Zeng X, Zhu S, Liu X, Zhou Y, Nussinov R, Cheng F. Zeng X, et al. Among authors: nussinov r. Bioinformatics. 2019 Dec 15;35(24):5191-5198. doi: 10.1093/bioinformatics/btz418. Bioinformatics. 2019. PMID: 31116390 Free PMC article.

9

A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling.

Huang Y, Fang J, Lu W, Wang Z, Wang Q, Hou Y, Jiang X, Reizes O, Lathia J, Nussinov R, Eng C, Cheng F. Huang Y, et al. Among authors: nussinov r. Cell Chem Biol. 2019 Aug 15;26(8):1143-1158.e6. doi: 10.1016/j.chembiol.2019.05.004. Epub 2019 Jun 6. Cell Chem Biol. 2019. PMID: 31178408 Free PMC article.

10

Correction: Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers.

Nussinov R, Jang H, Tsai CJ, Cheng F. Nussinov R, et al. PLoS Comput Biol. 2019 Jun 12;15(6):e1007114. doi: 10.1371/journal.pcbi.1007114. eCollection 2019 Jun. PLoS Comput Biol. 2019. PMID: 31188819 Free PMC article.

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