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Page 1
E7766, a Macrocycle-Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan-Genotypic Activity.
Kim DS, Endo A, Fang FG, Huang KC, Bao X, Choi HW, Majumder U, Shen YY, Mathieu S, Zhu X, Sanders K, Noland T, Hao MH, Chen Y, Wang JY, Yasui S, TenDyke K, Wu J, Ingersoll C, Loiacono KA, Hutz JE, Sarwar N. Kim DS, et al. Among authors: loiacono ka. ChemMedChem. 2021 Jun 7;16(11):1740-1743. doi: 10.1002/cmdc.202100068. Epub 2021 Feb 25. ChemMedChem. 2021. PMID: 33522135
Expression and isolation of antimicrobial small molecules from soil DNA libraries.
MacNeil IA, Tiong CL, Minor C, August PR, Grossman TH, Loiacono KA, Lynch BA, Phillips T, Narula S, Sundaramoorthi R, Tyler A, Aldredge T, Long H, Gilman M, Holt D, Osburne MS. MacNeil IA, et al. Among authors: loiacono ka. J Mol Microbiol Biotechnol. 2001 Apr;3(2):301-8. J Mol Microbiol Biotechnol. 2001. PMID: 11321587
Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms.
Rondon MR, August PR, Bettermann AD, Brady SF, Grossman TH, Liles MR, Loiacono KA, Lynch BA, MacNeil IA, Minor C, Tiong CL, Gilman M, Osburne MS, Clardy J, Handelsman J, Goodman RM. Rondon MR, et al. Among authors: loiacono ka. Appl Environ Microbiol. 2000 Jun;66(6):2541-7. doi: 10.1128/AEM.66.6.2541-2547.2000. Appl Environ Microbiol. 2000. PMID: 10831436 Free PMC article.
Structure-activity relationships of a novel class of Src SH2 inhibitors.
Buchanan JL, Vu CB, Merry TJ, Corpuz EG, Pradeepan SG, Mani UN, Yang M, Plake HR, Varkhedkar VM, Lynch BA, MacNeil IA, Loiacono KA, Tiong CL, Holt DA. Buchanan JL, et al. Among authors: loiacono ka. Bioorg Med Chem Lett. 1999 Aug 16;9(16):2359-64. doi: 10.1016/s0960-894x(99)00389-3. Bioorg Med Chem Lett. 1999. PMID: 10476869
A fluorescence polarization based Src-SH2 binding assay.
Lynch BA, Loiacono KA, Tiong CL, Adams SE, MacNeil IA. Lynch BA, et al. Among authors: loiacono ka. Anal Biochem. 1997 Apr 5;247(1):77-82. doi: 10.1006/abio.1997.2042. Anal Biochem. 1997. PMID: 9126374