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Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents.
Blanchard EL, Vanover D, Bawage SS, Tiwari PM, Rotolo L, Beyersdorf J, Peck HE, Bruno NC, Hincapie R, Michel F, Murray J, Sadhwani H, Vanderheyden B, Finn MG, Brinton MA, Lafontaine ER, Hogan RJ, Zurla C, Santangelo PJ. Blanchard EL, et al. Among authors: brinton ma. Nat Biotechnol. 2021 Jun;39(6):717-726. doi: 10.1038/s41587-021-00822-w. Epub 2021 Feb 3. Nat Biotechnol. 2021. PMID: 33536629
mRNA-encoded Cas13 can be used to treat dengue infections in mice.
Basu M, Zurla C, Auroni TT, Vanover D, Chaves LCS, Sadhwani H, Pathak H, Basu R, Beyersdorf JP, Amuda OO, Elsharkawy A, Mosur V, Arthur RA, Claussen H, Sasser LE, Wroe JA, Peck HE, Kumar M, Brinton MA, Santangelo PJ. Basu M, et al. Among authors: brinton ma. Nat Microbiol. 2024 Aug;9(8):2160-2172. doi: 10.1038/s41564-024-01726-6. Epub 2024 Jun 5. Nat Microbiol. 2024. PMID: 38839984
Structure of an RNA G-quadruplex from the West Nile virus genome.
Terrell JR, Le TT, Paul A, Brinton MA, Wilson WD, Poon GMK, Germann MW, Siemer JL. Terrell JR, et al. Among authors: brinton ma. Nat Commun. 2024 Jun 26;15(1):5428. doi: 10.1038/s41467-024-49761-5. Nat Commun. 2024. PMID: 38926367 Free PMC article.
128 results