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Procalcitonin, C-reactive protein, neutrophil gelatinase-associated lipocalin, resistin and the APTT waveform for the early diagnosis of serious bacterial infection and prediction of outcome in critically ill children.
Nielsen MJ, Baines P, Jennings R, Siner S, Kolamunnage-Dona R, Newland P, Peak M, Chesters C, Jeffers G, Downey C, Broughton C, McColl L, Preston J, McKeever A, Paulus S, Cunliffe N, Carrol ED. Nielsen MJ, et al. Among authors: downey c. PLoS One. 2021 Feb 5;16(2):e0246027. doi: 10.1371/journal.pone.0246027. eCollection 2021. PLoS One. 2021. PMID: 33544738 Free PMC article.
Biphasic transmittance waveform in the APTT coagulation assay is due to the formation of a Ca(++)-dependent complex of C-reactive protein with very-low-density lipoprotein and is a novel marker of impending disseminated intravascular coagulation.
Toh CH, Samis J, Downey C, Walker J, Becker L, Brufatto N, Tejidor L, Jones G, Houdijk W, Giles A, Koschinsky M, Ticknor LO, Paton R, Wenstone R, Nesheim M. Toh CH, et al. Among authors: downey c. Blood. 2002 Oct 1;100(7):2522-9. doi: 10.1182/blood.V100.7.2522. Blood. 2002. PMID: 12239165 Free article.
The clinical utility of fibrin-related biomarkers in sepsis.
Toh JM, Ken-Dror G, Downey C, Abrams ST. Toh JM, et al. Among authors: downey c. Blood Coagul Fibrinolysis. 2013 Dec;24(8):839-43. doi: 10.1097/MBC.0b013e3283646659. Blood Coagul Fibrinolysis. 2013. PMID: 24030119
232 results